Detalhe da pesquisa
1.
Defining a Cancer Dependency Map.
Cell
; 170(3): 564-576.e16, 2017 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28753430
2.
Cas9 activates the p53 pathway and selects for p53-inactivating mutations.
Nat Genet
; 52(7): 662-668, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32424350
3.
Author Correction: Cas9 activates the p53 pathway and selects for p53-inactivating mutations.
Nat Genet
; 52(7): 748-749, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-32587373
4.
A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma.
Cancer Res
; 79(9): 2352-2366, 2019 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30819666
5.
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.
Nat Commun
; 10(1): 5817, 2019 12 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31862961
6.
Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer.
Mol Cancer Res
; 17(11): 2281-2293, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31462500
7.
Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling.
Cancer Cell
; 34(6): 922-938.e7, 2018 12 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30537514
8.
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.
J Clin Invest
; 128(1): 446-462, 2018 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29202477
9.
Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.
Nat Genet
; 49(12): 1779-1784, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-29083409
10.
Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants.
Cell Rep
; 17(4): 1171-1183, 2016 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-27760319
11.
High-throughput Phenotyping of Lung Cancer Somatic Mutations.
Cancer Cell
; 30(2): 214-228, 2016 08 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27478040
12.
Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting.
Cancer Discov
; 6(8): 914-29, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27260156
13.
High-throughput Phenotyping of Lung Cancer Somatic Mutations.
Cancer Cell
; 32(6): 884, 2017 12 11.
Artigo
Inglês
| MEDLINE | ID: mdl-29232558