Detalhe da pesquisa
1.
Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91.
Mol Cell
; 84(5): 955-966.e4, 2024 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38325379
2.
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Nature
; 592(7856): 799-803, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33854232
3.
Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions.
Nat Methods
; 20(9): 1291-1303, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37400558
4.
Prediction of cancer driver genes and mutations: the potential of integrative computational frameworks.
Brief Bioinform
; 25(2)2024 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38261338
5.
TFG binds LC3C to regulate ULK1 localization and autophagosome formation.
EMBO J
; 40(10): e103563, 2021 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33932238
6.
A workflow to study mechanistic indicators for driver gene prediction with Moonlight.
Brief Bioinform
; 24(5)2023 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37551622
7.
MutateX: an automated pipeline for in silico saturation mutagenesis of protein structures and structural ensembles.
Brief Bioinform
; 23(3)2022 05 13.
Artigo
Inglês
| MEDLINE | ID: mdl-35323860
8.
DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation.
Nucleic Acids Res
; 50(D1): D480-D487, 2022 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34850135
9.
PDBminer to Find and Annotate Protein Structures for Computational Analysis.
J Chem Inf Model
; 63(23): 7274-7281, 2023 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37977136
10.
PyInteraph2 and PyInKnife2 to Analyze Networks in Protein Structural Ensembles.
J Chem Inf Model
; 63(14): 4237-4245, 2023 07 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37437128
11.
Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J Biol Chem
; 297(3): 101039, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34343569
12.
DisProt: intrinsic protein disorder annotation in 2020.
Nucleic Acids Res
; 48(D1): D269-D276, 2020 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31713636
13.
Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1.
Proc Natl Acad Sci U S A
; 116(14): 7123-7128, 2019 04 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30872479
14.
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.
Acta Neuropathol
; 142(3): 537-564, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34302498
15.
CAncer bioMarker Prediction Pipeline (CAMPP)-A standardized framework for the analysis of quantitative biological data.
PLoS Comput Biol
; 16(3): e1007665, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32176694
16.
Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration.
Breast Cancer Res
; 22(1): 73, 2020 06 30.
Artigo
Inglês
| MEDLINE | ID: mdl-32605588
17.
Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level.
PLoS Comput Biol
; 15(12): e1007485, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31825969
18.
New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx.
PLoS Comput Biol
; 15(3): e1006701, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30835723
19.
Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations.
PLoS Genet
; 13(4): e1006739, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28422960
20.
Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations.
Hum Mutat
; 40(4): 444-457, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30648773