Detalhe da pesquisa
1.
Design and testing of a humanized porcine donor for xenotransplantation.
Nature
; 622(7982): 393-401, 2023 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-37821590
2.
Kidney transplantation from triple-knockout pigs expressing multiple human proteins in cynomolgus macaques.
Am J Transplant
; 22(1): 46-57, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34331749
3.
Single-cell quantitative HER2 measurement identifies heterogeneity and distinct subgroups within traditionally defined HER2-positive patients.
Am J Pathol
; 183(5): 1446-1460, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24035511
4.
Extensive germline genome engineering in pigs.
Nat Biomed Eng
; 5(2): 134-143, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32958897
5.
Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunity.
Sci Transl Med
; 11(512)2019 10 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31578241
6.
Predicting ligand-dependent tumors from multi-dimensional signaling features.
NPJ Syst Biol Appl
; 3: 27, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28944080
7.
Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121).
NPJ Syst Biol Appl
; 3: 16034, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28725482
8.
Computational modeling of ERBB2-amplified breast cancer identifies combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors.
Sci Signal
; 6(288): ra68, 2013 Aug 13.
Artigo
Inglês
| MEDLINE | ID: mdl-23943608
9.
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.
Mol Cancer Ther
; 11(3): 582-93, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22248472
10.
Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.
Sci Signal
; 2(77): ra31, 2009 Jun 30.
Artigo
Inglês
| MEDLINE | ID: mdl-19567914
11.
Purification and characterization of a recombinant version of human alpha-fetoprotein expressed in the milk of transgenic goats.
Protein Expr Purif
; 38(2): 177-83, 2004 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-15555933
12.
GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells.
Immunity
; 18(4): 535-47, 2003 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-12705856