[Karyotype studies in cases of hereditary hypodontia]. / Indagini sul cariotipo in casi di ipodontia ereditaria.

The Authors examined 22 families (including 67 individuals) in whose components one or more teeth were found to be congenitally missing. The morphological characteristics of the chromosomes were analyzed with the technique of Moorhead to observe any aberration in shape, size and pattern. With such method, no alteration of the karyotype was shown in case of oligodontia.

[Clinico-experimental study of a new antibactorial agent for local use in stomatology]. / Contributo clinico-sperimentale allo studio di un nuovo antibatterico per uso locale in stomatologia

Tibezonium iodide is a new drug having antibacterial activity for the therapy and the prevention of mouth infections. Before testing its therapeutic efficacy, its effect on the bacterial flora of the human saliva was verified as follows. Salivary samples, collected before and after the administration (double-blind, cross-over) to volunteers, were counted for bacteria. The drug reduced the bacterial count in the saliva with statistical significance in both the pharmaceutical forms. Subsequently the drug was tested in different dental or oral conditions. To 90 patients suffering from marginal paradentitis or other diseases with this type of complications tablets were administered. The results obtained in this group were satisfactory or almost satisfactory in 73.5% of the cases examined. The patients treated with bubble-gums were 70. All of them were suffering from the same kind of disease of the first group; a few of them had alveolitis following tooth extraction. The results in these subjects were satisfactory or almost satisfactory in 77% of the cases examined. Tibezonium proved to be particularly effective in marginal paradentitis and in piorrhoic paradontosis. Bubble-gums should not be used in subjects with dental mobile prosthesis.