Detalhe da pesquisa
1.
The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size.
J Biol Chem
; 298(10): 102370, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35970390
2.
Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells.
J Biol Chem
; 298(1): 101477, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34896393
3.
Eph-ephrin bidirectional signaling in physiology and disease.
Cell
; 133(1): 38-52, 2008 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-18394988
4.
A cancer mutation promotes EphA4 oligomerization and signaling by altering the conformation of the SAM domain.
J Biol Chem
; 297(1): 100876, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34139238
5.
Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis.
J Neurosci
; 40(31): 5908-5921, 2020 07 29.
Artigo
Inglês
| MEDLINE | ID: mdl-32601248
6.
Ligand bias in receptor tyrosine kinase signaling.
J Biol Chem
; 295(52): 18494-18507, 2020 12 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33122191
7.
A cellular target engagement assay for the characterization of SHP2 (PTPN11) phosphatase inhibitors.
J Biol Chem
; 295(9): 2601-2613, 2020 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-31953320
8.
Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J Biol Chem
; 294(22): 8791-8805, 2019 05 31.
Artigo
Inglês
| MEDLINE | ID: mdl-31015204
9.
The SAM domain inhibits EphA2 interactions in the plasma membrane.
Biochim Biophys Acta Mol Cell Res
; 1864(1): 31-38, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-27776928
10.
Eph receptors and ephrins: therapeutic opportunities.
Annu Rev Pharmacol Toxicol
; 55: 465-87, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25292427
11.
A small peptide promotes EphA2 kinase-dependent signaling by stabilizing EphA2 dimers.
Biochim Biophys Acta
; 1860(9): 1922-8, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27281300
12.
Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery.
Int J Mol Sci
; 18(2)2017 Feb 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28165374
13.
EphA2 Receptor Unliganded Dimers Suppress EphA2 Pro-tumorigenic Signaling.
J Biol Chem
; 290(45): 27271-27279, 2015 Nov 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26363067
14.
Unliganded EphA3 dimerization promoted by the SAM domain.
Biochem J
; 471(1): 101-9, 2015 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26232493
15.
Association of the breast cancer antiestrogen resistance protein 1 (BCAR1) and BCAR3 scaffolding proteins in cell signaling and antiestrogen resistance.
J Biol Chem
; 289(15): 10431-10444, 2014 Apr 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24584939
16.
Targeting Eph receptors with peptides and small molecules: progress and challenges.
Semin Cell Dev Biol
; 23(1): 51-7, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22044885
17.
Ephrin-A1/EphA4-mediated adhesion of monocytes to endothelial cells.
Biochim Biophys Acta
; 1833(10): 2201-11, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23707953
18.
Eph receptors and ephrins in cancer progression.
Nat Rev Cancer
; 24(1): 5-27, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-37996538
19.
Inhibition of Ephrin B2 Reverse Signaling Abolishes Multiple Myeloma Pathogenesis.
Cancer Res
; 84(6): 919-934, 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38231476
20.
The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway.
Nat Cell Biol
; 8(8): 815-25, 2006 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-16862147