Detalhe da pesquisa
1.
Design, synthesis and biological evaluation of novel pyrazolo-pyrimidin-amines as potent and selective BTK inhibitors.
Bioorg Chem
; 130: 106238, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36403335
2.
Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor.
Bioorg Med Chem Lett
; 66: 128728, 2022 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35413417
3.
Discovery of a potent G-protein-coupled receptor 119 agonist for the treatment of type 2 diabetes.
Bioorg Med Chem
; 35: 116071, 2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33611013
4.
Discovery of diaminopyrimidine-carboxamide derivatives as JAK3 inhibitors.
Bioorg Chem
; 99: 103851, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32334196
5.
ZYBT1, a potent, irreversible Bruton's Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer.
Pharmacol Res Perspect
; 8(4): e00565, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32790160