Detalhe da pesquisa
1.
Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.
PLoS Pathog
; 11(7): e1005035, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-26161532
2.
A novel investigational Fc-modified humanized monoclonal antibody, motavizumab-YTE, has an extended half-life in healthy adults.
Antimicrob Agents Chemother
; 57(12): 6147-53, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24080653
3.
Natural polymorphisms and resistance-associated mutations in the fusion protein of respiratory syncytial virus (RSV): effects on RSV susceptibility to palivizumab.
J Infect Dis
; 205(4): 635-8, 2012 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22184728
4.
Analysis of respiratory syncytial virus preclinical and clinical variants resistant to neutralization by monoclonal antibodies palivizumab and/or motavizumab.
J Infect Dis
; 203(5): 674-82, 2011 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21208913
5.
Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract.
J Mol Biol
; 368(3): 652-65, 2007 May 04.
Artigo
Inglês
| MEDLINE | ID: mdl-17362988
6.
A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med
; 9(388)2017 05 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28469033
7.
Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization.
J Mol Biol
; 350(1): 126-44, 2005 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15907931
8.
Identification of antibody neutralization epitopes on the fusion protein of human metapneumovirus.
J Gen Virol
; 89(Pt 12): 3113-3118, 2008 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-19008400
9.
Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo.
J Virol
; 80(16): 7799-806, 2006 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-16873237
10.
Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.
J Immunol
; 169(9): 5171-80, 2002 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-12391234
11.
Surveillance of clinical isolates of respiratory syncytial virus for palivizumab (Synagis)-resistant mutants.
J Infect Dis
; 190(5): 975-8, 2004 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15295704