RESUMO
Pulmonary carcinoid tumors are uncommon neuroendocrine tumors that rarely metastasize to the skin. We report the case of a 71-year-old woman with a longstanding history of primary atypical pulmonary carcinoid tumor who presented with a new tender cutaneous nodule. Immunostaining of the nodule was consistent with metastatic atypical carcinoid tumor of the skin including positive staining for neuroendocrine markers chromogranin and synaptophysin. Dermatologists should consider cutaneous neuroendocrine metastasis when evaluating new nodules in patients with stable pulmonary carcinoid tumors or in those with concomitant concerning respiratory symptoms.
Assuntos
Tumor Carcinoide/secundário , Neoplasias Pulmonares/patologia , Neoplasias Cutâneas/secundário , Tela Subcutânea , Idoso , Feminino , HumanosAssuntos
Ansiedade , Couro Cabeludo , Alopecia/diagnóstico , Ansiedade/etiologia , Humanos , Percepção , FotografaçãoAssuntos
Doenças do Cabelo , Pessoas Transgênero , Transexualidade , Feminino , Identidade de Gênero , Cabelo , Humanos , MasculinoAssuntos
Couro Cabeludo , Realidade Virtual , Estudos Cross-Over , Humanos , Injeções , Manejo da DorAssuntos
Líquen Plano , Alopecia , Humanos , Líquen Plano/radioterapia , Projetos Piloto , Estudos Prospectivos , Couro CabeludoAssuntos
Alopecia , Couro Cabeludo , Alopecia/diagnóstico , Ansiedade/diagnóstico , Humanos , Percepção , FotografaçãoAssuntos
COVID-19 , Tricotilomania , Estudos Transversais , Humanos , Pandemias , SARS-CoV-2 , EstudantesAssuntos
Anormalidades Induzidas por Medicamentos/prevenção & controle , COVID-19 , Fármacos Dermatológicos/efeitos adversos , Isotretinoína/efeitos adversos , Formulação de Políticas , Testes de Gravidez , Gestão de Riscos , Telemedicina , Teratogênicos , Anormalidades Induzidas por Medicamentos/etiologia , Feminino , Humanos , Gravidez , Medição de Risco , Fatores de Risco , UrináliseAssuntos
Queimaduras/complicações , Cicatriz/cirurgia , Current Procedural Terminology , Terapia a Laser/economia , Ferimentos e Lesões/complicações , Adulto , Fatores Etários , Superfície Corporal , Criança , Cicatriz/diagnóstico , Cicatriz/economia , Cicatriz/etiologia , Humanos , Lactente , Reembolso de Seguro de Saúde/normas , Terapia a Laser/instrumentação , Lasers de Gás/uso terapêutico , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
BACKGROUND AND OBJECTIVES: Gender-affirming hormone therapy (GAHT) is a key component in the primary care of transgender and gender-nonconforming (TGNC) people. However, physicians are hesitant to initiate GAHT, citing a lack of knowledge. We developed an educational program for medical students and sought to investigate whether medical students' comfort and familiarity with GAHT could increase after a short interactive program. METHODS: Second-year medical students (N=54) at the University of Minnesota were recruited to attend an hour long interactive lecture on GAHT. We calculated mean change in pre- and postintervention 5-point Likert scale scores from a survey assessing comfort and familiarity with key concepts of GAHT to assess the effectiveness of the intervention. RESULTS: Mean response score change increased significantly after the intervention around the use of chosen names (0.4±0.13, P<.017), the use of informed consent to initiate GAHT (1.8±0.20, P<.001), initiating and managing GAHT in the primary care setting (1.4±0.19, P<.001), medications used in GAHT (2.3±0.21, P<.001), and dosing (2.5±0.60, P<.001). CONCLUSIONS: GAHT can be initiated and managed in a primary care setting. There is a push to introduce GAHT in the preclinical years. After participating in a short interactive lecture on GAHT, second-year medical students reported increased comfort and familiarity with GAHT. Inclusion of GAHT in the preclinical curriculum does not require significant teaching time and is important knowledge for all future physicians.
Assuntos
Estudantes de Medicina , Pessoas Transgênero , Currículo , Hormônios , HumanosRESUMO
Treatment options for hair loss have traditionally been limited to topical and systemic therapies. Systemic therapies for inflammatory hair disorders are often immunosuppressive, and systemic treatment of androgenetic hair loss can cause undesired effects on sexual and reproductive health. Topical agents have a favorable side effect profile compared with systemic therapies, but many topicals have poor transcutaneous absorption, limiting their concentration and action at follicular targets in the dermis.