1.
Org Biomol Chem
; 11(40): 6874-8, 2013 Sep 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23986144
RESUMO
A simple method for the synthesis of a sugar furanoid trans vicinal diacid and its incorporation into the N-terminal tetrapeptide sequence (H-Phe-Trp-Lys-Thr-OH) to get glycopeptide has been described. 2D NMR and MD simulation studies of clearly show that the sugar diacid adopts a γ-turn conformation towards the N-terminus.