Detalhe da pesquisa
1.
The cryo-electron microscopy structure of huntingtin.
Nature
; 555(7694): 117-120, 2018 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29466333
2.
Covalent inhibitor reactivity prediction by the electrophilicity index-in and out of scope.
J Comput Aided Mol Des
; 35(4): 531-539, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33015740
3.
BIreactive: A Machine-Learning Model to Estimate Covalent Warhead Reactivity.
J Chem Inf Model
; 60(6): 2915-2923, 2020 06 22.
Artigo
Inglês
| MEDLINE | ID: mdl-32250627
4.
A Fast Ab Initio Predictor Tool for Covalent Reactivity Estimation of Acrylamides.
J Chem Inf Model
; 59(8): 3565-3571, 2019 08 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31246457
5.
Fast native-SAD phasing for routine macromolecular structure determination.
Nat Methods
; 12(2): 131-3, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25506719
6.
Structure of a nanobody-stabilized active state of the ß(2) adrenoceptor.
Nature
; 469(7329): 175-80, 2011 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-21228869
7.
Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis.
Eur Respir J
; 45(5): 1434-45, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25745043
8.
Crystal structure of glucokinase regulatory protein.
Biochemistry
; 52(20): 3523-31, 2013 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23621087
9.
Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design.
Acta Crystallogr D Struct Biol
; 79(Pt 10): 871-880, 2023 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37712434
10.
Molecular basis of TASL recruitment by the peptide/histidine transporter 1, PHT1.
Nat Commun
; 14(1): 5696, 2023 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37709742
11.
A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems.
Protein Expr Purif
; 82(2): 308-16, 2012 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-22342679
12.
Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism.
ACS Chem Biol
; 17(4): 816-821, 2022 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35377598
13.
Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex.
Structure
; 29(8): 804-809.e5, 2021 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33909994
14.
Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists.
Structure
; 27(3): 427-438.e5, 2019 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30581043
15.
C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins.
Naunyn Schmiedebergs Arch Pharmacol
; 374(5-6): 347-60, 2007 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-17146673
16.
Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib.
ACS Chem Biol
; 11(6): 1595-602, 2016 06 17.
Artigo
Inglês
| MEDLINE | ID: mdl-26999302
17.
Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy.
Cryst Growth Des
; 14(4): 2034-2047, 2014 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-24803849
18.
The Implication of the First Agonist Bound Activated GPCR X-ray Structure on GPCR in Silico Modeling.
ACS Med Chem Lett
; 2(6): 414-8, 2011 Jun 09.
Artigo
Inglês
| MEDLINE | ID: mdl-24900322
19.
Molecular recognition of the protein phosphatase 1 glycogen targeting subunit by glycogen phosphorylase.
J Biol Chem
; 283(14): 8913-8, 2008 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-18198182
20.
Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
EMBO J
; 24(20): 3670-80, 2005 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-16177825