RESUMO
To determine the accuracy of computed tomography (CT) of the chest in the staging of lung cancer, we studied 418 patients with primary pulmonary carcinoma between 1979 and 1986. Each had a preoperative scan performed before detailed operative staging. Each CT scan was analyzed for components of the current TNM staging system. Computed tomography sensitivity and specificity for mediastinal lymph node metastasis were 84.4% and 84.1%, with corresponding positive and negative predictive accuracies of 68.7% and 92.9%, respectively. When TNM stages were derived from CT scans, only 190 of 418 (45.4%) completely agreed with operative staging. An additional 53 of 418 (12.7%) predicted the correct stage, although components of the TNM system were incorrect. In 94 of 418 scans (22.5%) CT overestimated the stage, whereas in 81 (19.4%) CT downgraded the stage. Computed tomography suggested metastatic lesions in liver, lung, adrenal gland, bone, or abdominal lymph nodes in 40 of 373 scans (10.7%); only five of 40 (12.5%) had documented metastasis. In summary, CT of the chest cannot accurately stage primary lung carcinoma according to the TNM classification. Because the negative predictive accuracy for mediastinal lymph node metastasis remains high (92.9%), invasive staging can be deferred for definitive thoracotomy when no lymphadenopathy is evident on CT. The high negative predictive accuracy for scans of the chest and upper abdomen makes CT a useful tool for exclusion of metastatic disease.
Assuntos
Neoplasias Pulmonares/patologia , Tomografia Computadorizada por Raios X , Adenocarcinoma/diagnóstico por imagem , Adenocarcinoma/patologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma/diagnóstico por imagem , Carcinoma/patologia , Carcinoma de Células Escamosas/diagnóstico por imagem , Carcinoma de Células Escamosas/patologia , Feminino , Humanos , Neoplasias Pulmonares/diagnóstico por imagem , Linfonodos/patologia , Metástase Linfática , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Valor Preditivo dos Testes , Sensibilidade e Especificidade , Tomógrafos ComputadorizadosRESUMO
As only a few cases of intrathoracic thyroid malignancy with computed tomographic (CT) examination have been described, we reviewed the CT examinations of three patients with primary and five patients with recurrent thyroid malignancy involving the thorax. Irregular border of the thyroid mass, extension of tumor mass into mediastinal fat or chest wall, or lymphadenopathy suggested the malignant nature of the primary tumor. CT examination in recurrent disease demonstrated mediastinal, hilar and retrocrural adenopathy, compression of major vessels with collateral flow, pulmonary and bony metastases. CT was of value both in identifying the extent of disease and documenting response to treatment.
Assuntos
Neoplasias do Mediastino/diagnóstico por imagem , Neoplasias da Glândula Tireoide/diagnóstico por imagem , Adenocarcinoma/diagnóstico por imagem , Adenocarcinoma/secundário , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma Papilar/diagnóstico por imagem , Carcinoma Papilar/secundário , Humanos , Linfonodos/diagnóstico por imagem , Metástase Linfática , Neoplasias do Mediastino/secundário , Mediastino/diagnóstico por imagem , Pessoa de Meia-Idade , Radiografia , Neoplasias da Glândula Tireoide/secundárioRESUMO
A patient with esophageal intramural pseudodiverticulosis (EIPD) was examined with computed tomography (CT). CT demonstrated marked thickening of the esophageal wall, diffuse irregularity of the esophageal lumen, and intramural gas collections--features typical of this entity. In the proper clinical setting, CT can confirm the diagnosis of EIPD, especially when other studies are equivocal. However, this case also demonstrates some of the limitations of CT in differentiating benign and malignant esophageal disorders.
Assuntos
Divertículo Esofágico/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Esôfago/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
The ultrasonic features in three cases and computed tomographic (CT) findings in one case of mucocele of the appendix are presented. This entity appeared cystic on sonography and may have high-intensity echoes within it. The wall was not thickened and did not contain calcification, unlike previous descriptions. On CT, the mass was of soft tissue density, while previously, it had been described as cystic. Although mucocele of the appendix has a more variable appearance on sonography and CT than previously reported, a correct preoperative diagnosis can be made in most cases. Barium enema examination or calcification in the wall or in the mass itself may be necessary to distinguish this entity from lymphoma if the lesion is of soft tissue density on CT.
Assuntos
Apêndice , Mucocele/diagnóstico , Tomografia Computadorizada por Raios X , Ultrassonografia , Idoso , Apêndice/diagnóstico por imagem , Doenças do Ceco/diagnóstico , Doenças do Ceco/diagnóstico por imagem , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Mucocele/diagnóstico por imagemRESUMO
The occurrence rate of renal cell carcinoma is significantly higher in the native kidneys of patients undergoing chronic hemodialysis than in kidneys of normal subjects. These carcinomas may be difficult to detect because these kidneys tend to be small and distorted owing to acquired cystic disease. Four cases of renal cell carcinoma detected by CT are presented (three in patients undergoing chronic hemodialysis, and one in a patient with a functioning transplant who had history of dialysis). All kidneys had extensive acquired cystic disease. In two cases, contrast-enhanced scans showed a solid lesion of lower density than the kidney. In another case, in which IV contrast material could not be given, the mass was of higher density than the kidney and retroperitoneal lymphadenopathy was present. In the fourth case, no distinct solid mass could be identified. The only sign of malignancy in this case was extensive lymphadenopathy. Whenever CT examination of the abdomen is performed in a patient undergoing chronic hemodialysis, the kidneys must be evaluated carefully because of the increased frequency of renal cell carcinoma. In a few cases, a distinct solid lesion may not be apparent or may be subtle owing to distortion of renal anatomy by acquired cystic disease.
Assuntos
Carcinoma de Células Renais/diagnóstico por imagem , Neoplasias Renais/diagnóstico por imagem , Diálise Renal/efeitos adversos , Tomografia Computadorizada por Raios X , Idoso , Carcinoma de Células Renais/etiologia , Humanos , Neoplasias Renais/etiologia , Masculino , Pessoa de Meia-IdadeRESUMO
Laser therapy is a new modality for treatment of airway lesions. We examined 18 patients prior to laser photoresection of tracheobronchial lesions. Thirteen had cancers involving the distal trachea, carina, and/or proximal bronchi; five had benign lesions of the middle or proximal trachea. Each patient was examined by conventional linear tomography (CLT) and computed tomography (CT). CT was valuable in patients who had lesions of the distal trachea, carina, and/or proximal bronchi. Its particular usefulness, and its advantage relative to CLT, consisted in its ability to delineate vascular structures adjacent to the planned area of photoresection. Neither CLT nor CT was helpful in evaluation of benign lesions of the proximal trachea.
Assuntos
Neoplasias Brônquicas/diagnóstico por imagem , Terapia a Laser , Tomografia Computadorizada por Raios X , Tomografia por Raios X , Neoplasias da Traqueia/diagnóstico por imagem , Idoso , Neoplasias Brônquicas/cirurgia , Broncoscopia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias da Traqueia/cirurgiaRESUMO
We reviewed medical records and conventional chest radiographs that showed a solitary T1N0M0 nodule in 23 patients who had non-oat-cell bronchogenic carcinoma. No patient had evidence of metastases, either on the chest radiograph or clinically. All patients underwent computed tomography (CT) examination of the thorax, including the adrenal glands. Only one patient (4%) had mediastinal lymph nodes greater than 1 cm in diameter accessible to mediastinotomy; anterior mediastinotomy confirmed metastatic spread in this patient, which precluded curative resection. Three patients each had a mildly enlarged (2 cm or less) adrenal gland; however, follow-up study suggested that metastasis was not the cause of adrenal enlargement in these patients. This study reinforces concern over whether CT is warranted in the preoperative assessment of T1N0M0 bronchogenic carcinoma.
Assuntos
Carcinoma Broncogênico/diagnóstico por imagem , Neoplasias Pulmonares/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adenocarcinoma/diagnóstico por imagem , Adulto , Idoso , Carcinoma de Células Escamosas/diagnóstico por imagem , Feminino , Humanos , Metástase Linfática , Masculino , Pessoa de Meia-Idade , Metástase Neoplásica , Cuidados Pré-Operatórios , Radiografia TorácicaRESUMO
Four cases of peptic ulcer penetrating the head of the pancreas were diagnosed by computed tomography (CT). Findings common to 3 cases included (a) an ulcer crater, (b) a sinus tract, and (c) enlargement of the head of the pancreas. Additional findings, not seen in all patients, included (d) edema involving the base of the ulcer and/or the adjacent bowel wall and (e) loss of fascial planes between the base of the ulcer and the head of the pancreas. Unlike other modalities, the inherent spatial resolution of CT allows a confident diagnosis of this important complication of peptic ulcer disease.
Assuntos
Úlcera Péptica/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Idoso , Feminino , Humanos , Pessoa de Meia-Idade , Pancreatopatias/diagnóstico por imagemRESUMO
CT examinations in 37 patients with proved small-cell bronchogenic carcinoma studied before treatment were reviewed. The distribution of lymphadenopathy in the mediastinal compartments designated by the American Thoracic Society was assessed. The frequency of lymph node enlargement was right hilum (43%), left hilum (49%), one or both hila (84%), right upper paratracheal (32%), right lower paratracheal (54%), right tracheobronchial (65%), left upper paratracheal (14%), left lower paratracheal (38%), left peribronchial (35%), paraesophageal (14%), anterior mediastinum (24%), and subcarinal (65%). We also assessed the frequency of additional findings including pleural effusion (38%), pericardial thickening (38%), displacement or narrowing of either the tracheobronchial tree (68%) or major vessels (68%), and hepatic masses (24%). Mediastinal involvement was present in 92% of cases, as compared with 13% reported in a large series based on conventional radiography. These data show the spectrum of intrathoracic CT findings in proved, untreated cases of small-cell bronchogenic carcinoma.
Assuntos
Carcinoma Broncogênico/diagnóstico por imagem , Carcinoma de Células Pequenas/diagnóstico por imagem , Neoplasias Pulmonares/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
We reviewed the CT of 20 patients with peripheral lung malignancies in which CT appearance suggested chest wall invasion on the basis of extension of mass around ribs into fat or muscle of the chest wall, or definite bone destruction. We correlated these findings with other radiographic studies and surgical and autopsy results. All 11 cases in which CT indicated chest wall involvement on the basis of definite bone destruction were confirmed. Tumor extension into the chest wall was disproven in six of the remaining nine cases in which invasion was suggested on the basis of tumor infiltration between ribs or extension of tumor into fat or soft tissue planes. Our findings confirm the lack of reliability of CT findings in determining the extension of malignancy into the chest wall, except when definite bone destruction is present.
Assuntos
Neoplasias Torácicas/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adenocarcinoma/diagnóstico por imagem , Tecido Adiposo/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma/diagnóstico por imagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Pleurais/diagnóstico por imagem , Costelas/diagnóstico por imagemRESUMO
Nineteen patients with bronchogenic carcinoma were studied by MR imaging to determine the presence of chest-wall invasion. All studies were carried out at 1.5 T, and the results were correlated with chest radiographs or CT scans. All MR studies were interpreted before surgery (13 cases) and without knowledge of the results of other radiologic studies. MR findings indicative of chest-wall invasion included a high-signal focus within the chest wall and/or chest-wall thickening with increased signal on spin-echo (SE) images having a repetition time of 2500 msec and an echo time of 50-100 msec (SE 2500/50-100). In one case, noncontour-deforming high-signal intensity within chest-wall musculature (but no other abnormality) was demonstrated on SE 2500/50-100 images. Coronal or sagittal imaging facilitated identification of tumor contiguity with extrathoracic structures in apical lesions. Contrast differences between normal and invaded chest wall on T2-weighted images were the most helpful in assessing chest-wall involvement. These preliminary observations indicate that MR imaging is useful in the evaluation of chest-wall invasion by carcinoma of the lung.