Natural history of prostate cancer.

Prostatic cancer can be a silent tumor, with no symptoms remaining undetectable throughout life . But when it keeps growing, enough to produce symptoms such as bladder neck obstruction, invasion of adjacent organs or distant metastasis, curative treatment is usually impossible. Since PSA emerges, data shows a dramatic increasing in the diagnosis of prostatic cancer, specially low risk tumor. Since then, We are wondering which tumors are suitable to be treated and which ones remain asymptomatic without treatment. Analysing the natural history of prostate cancer, helps us to choose the best atitude treating the tumor, this subjet has been in constant discusión in the last decade. Our article consistes of a reviewing the main publications treating natural history of prostate cancer in prehyphen;and post-PSA era. The indicated studied suggest that most prostate tumors diagnosed today are low grade cancer, as a result with a low mortality. This conclusión shows us the importance of modifying the algorithm of treatment of these tumors.

Historia natural del cáncer de próstata / Natural history of prostate cancer

El cáncer de próstata puede ser un tumor indolente, que no presenta síntomas y permanecer indetectable a lo largo de la vida. Pero cuando ha crecido lo suficiente como para producir sintomatología como obstrucción infravesical, invasión de órganos vecinos o metástasis a distancia, la curación es habitualmente imposible. La aparición del PSA ha supuesto un incremento dramático en el diagnóstico de los tumores de próstata de bajo riesgo. Todos nos preguntamos cuáles son los tumores que debemos de tratar y cuáles son los tumores que permanecerán asintomáticos. Conocer la historia natural del cáncer de próstata, nos ayudará a indicar correctamente su tratamiento, que en la actualidad está en permanente discusión. Realizamos en este trabajo una revisión de los principales estudios publicados en la literatura sobre la historia natural del cáncer de próstata en la era pre y post-PSA. Los datos que tenemos sugieren que la mayoría de los tumores de próstata que diagnosticamos en la actualidad son de bajo grado y por lo tanto con una baja mortalidad. Es necesario replantearse el algoritmo del tratamiento de estos tumores

Prostatic cancer can be a silent tumor, with no symptoms remaining undetectable throughout life. But when it keeps growing, enough to produce symptoms such as bladder neck obstruction, invasion of adjacent organs or distant metastasis, curative treatment is usually impossible. Since PSA emerges, data shows a dramatic increasing in the diagnosis of prostatic cancer, specially low risk tumor. Since then, We are wondering which tumors are suitable to be treated and which ones remain asymptomatic without treatment. Analysing the natural history of prostate cancer, helps us to choose the best atitude treating the tumor, this subjet has been in constant discusión in the last decade. Our article consistes of a reviewing the main publications treating natural history of prostate cancer in pre-and post- PSA era. The indicated studied suggest that most prostate tumors diagnosed today are low grade cancer, as a result with a low mortality. This conclusión shows us the importance of modifying the algorithm of treatment of these tumors