Detalhe da pesquisa
1.
Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity.
Hum Mol Genet
; 33(9): 818-834, 2024 Apr 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38641551
2.
Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia.
Haematologica
; 108(10): 2652-2663, 2023 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37021532
3.
Clinical and laboratory results in vaginal wall restoration using a fractional-pixel-CO2 laser: histological findings and changes in the Ki67 protein and telomere length.
Lasers Med Sci
; 38(1): 206, 2023 Sep 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37682379
4.
GSE4-loaded nanoparticles a potential therapy for lung fibrosis that enhances pneumocyte growth, reduces apoptosis and DNA damage.
FASEB J
; 35(3): e21422, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33638895
5.
Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis.
Immun Ageing
; 19(1): 7, 2022 Jan 27.
Artigo
Inglês
| MEDLINE | ID: mdl-35086525
6.
Shorter telomere length is associated with COVID-19 hospitalization and with persistence of radiographic lung abnormalities.
Immun Ageing
; 19(1): 38, 2022 Aug 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35996190
7.
Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening.
Hum Mol Genet
; 26(10): 1900-1914, 2017 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28369633
8.
Understanding the evolving phenotype of vascular complications in telomere biology disorders.
Angiogenesis
; 22(1): 95-102, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30168024
9.
Role of Dusp6 Phosphatase as a Tumor Suppressor in Non-Small Cell Lung Cancer.
Int J Mol Sci
; 20(8)2019 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31027181
10.
Impact of Nucleos(t)ide Reverse Transcriptase Inhibitors on Blood Telomere Length Changes in a Prospective Cohort of Aviremic HIV-Infected Adults.
J Infect Dis
; 218(10): 1531-1540, 2018 10 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29912427
11.
Platinum iodido drugs show potential anti-tumor activity, affecting cancer cell metabolism and inducing ROS and senescence in gastrointestinal cancer cells.
Commun Biol
; 7(1): 353, 2024 Mar 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38519773
12.
The dual-specificity protein phosphatase MkpB, homologous to mammalian MKP phosphatases, is required for D. discoideum post-aggregative development and cisplatin response.
Differentiation
; 81(3): 199-207, 2011 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-21300429
13.
Targeted cargo delivery in senescent cells using capped mesoporous silica nanoparticles.
Angew Chem Int Ed Engl
; 51(42): 10556-60, 2012 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22996839
14.
Choline Kinase α Inhibitors MN58b and RSM932A Enhances the Antitumor Response to Cisplatin in Lung Tumor Cells.
Pharmaceutics
; 14(6)2022 May 27.
Artigo
Inglês
| MEDLINE | ID: mdl-35745716
15.
Comparison of Colorectal Cancer Stem Cells and Oxaliplatin-Resistant Cells Unveils Functional Similarities.
Cells
; 11(3)2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35159320
16.
Harnessing PM2.5 Exposure Data to Predict Progression of Fibrotic Interstitial Lung Diseases Based on Telomere Length.
Front Med (Lausanne)
; 9: 871898, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35646972
17.
Translational proteomics: what can you do for true patients?
J Proteome Res
; 10(1): 101-4, 2011 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-20977278
18.
Early p38 Activation Regulated by MKP-1 Is Determinant for High Levels of IL-10 Expression Through TLR2 Activation.
Front Immunol
; 12: 660065, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34234775
19.
Selective T-cell depletion targeting CD45RA as a novel approach for HLA-mismatched hematopoietic stem cell transplantation in pediatric nonmalignant hematological diseases.
Int J Hematol
; 114(1): 116-123, 2021 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-33772729
20.
Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1.
Stem Cell Res Ther
; 12(1): 92, 2021 01 29.
Artigo
Inglês
| MEDLINE | ID: mdl-33514435