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1.
BMC Med Res Methodol ; 23(1): 192, 2023 08 22.
Artigo em Inglês | MEDLINE | ID: mdl-37608353

RESUMO

A multiple dependent state sampling plan (MDSSP) is designed when the lifetimes of the variables follow New Lomax Rayleigh Distribution (NLRD). The decision to accept or reject a lot in the proposed methodology is based on the quality of the given present or previous lots. A binomial model-based operating characteristic curve (OC curve) for continuous lots of variables under similar settings in healthcare is used in finding the probability of acceptance, acceptance number, rejection number, and the number of preceding (succeeding) lots to consider. Time truncated life test based on the specified median of the NLRD is used in designing the current acceptance sampling plan. For specified values of the parameters of NLRD, quantile ratios, consumer's risk and producer's risk, average sampling number (ASN) and probability of acceptance of a lot are reported in tables. Real data on worldwide suicide rates of 15-19 years in the year 2019 from the World Health Organization (WHO) website is considered to illustrate this methodology. The minimum sample size required from the selected data to comment on worldwide suicide rates in late adolescents is explained with MDSSP. The results of the proposed acceptance sampling method are compared with the single-stage sampling plan.


Assuntos
Modelos Estatísticos , Suicídio , Humanos , Adolescente , Probabilidade , Tamanho da Amostra , Organização Mundial da Saúde
2.
Heliyon ; 10(6): e27376, 2024 Mar 30.
Artigo em Inglês | MEDLINE | ID: mdl-38515696

RESUMO

The effectiveness of the parental distribution is modified in this article by adding flexibility, allowing it to capture all characteristics of the provided real-world data sets. This is accomplished by using the T-X class of distributions to generalize the parental distribution. Odd Lomax log-logistic distribution or OLLLD in short, is the name of the generalized parental distribution. The fundamental statistical properties of OLLLD are explicitly expressed. The maximum likelihood estimation approach is used to estimate the unidentified OLLLD parameters. In order to investigate the fit of the approach employed in estimating the parameters of OLLLD, the data are generated and an investigation done. Again, the ability of OLLLD is evaluated by fitting it to the real survival time data set of breast cancer.

3.
PLoS Negl Trop Dis ; 18(2): e0011631, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38315727

RESUMO

In 2021, a comprehensive dog demographic questionnaire combined with a KAP survey were conducted in the northern communal areas (NCAs) of Namibia with the aim of gaining a better understanding of dog populations, owner behaviour, and knowledge, attitudes and practices (KAP) relating to rabies. The survey of 3,726 households across the eight regions of the NCAs provided insights that will inform interventions in order to improve human rabies prevention and Namibia's dog rabies control strategy. The results showed a relatively low average human/dog ratio (HDR) of 5.4:1 indicating a surprisingly high dog population of at least 272,000 dogs in the NCAs, 93% of which appear to be owned but are free-roaming. Data analysis revealed opportunities but also highlighted needs for improvements in rabies surveillance and mass dog vaccinations. Although knowledge, attitude, and practice scores towards epidemiologic and clinical aspects, human rabies prevention, and dog rabies vaccination were deemed to be acceptable, the survey nevertheless revealed deficiencies in certain aspects in some of the population. Interestingly, data seemed to indicate relatively high dog bite incidences per 100,000 people, ranging between 262 and 1,369 and a certain number of unreported human rabies cases. Despite the very high number of dogs, only 50% of dog-owning households reported having vaccinated their dogs. In order to address these issues, the planning, announcement, and implementation of mass dog vaccination campaigns needs to be adapted to achieve adequate vaccination coverage. Another focus needs to be on rabies awareness and education if Namibia is to be significantly contributing to the global goal of "Zero by 30".


Assuntos
Doenças do Cão , Vacina Antirrábica , Raiva , Animais , Humanos , Cães , Raiva/epidemiologia , Raiva/prevenção & controle , Raiva/veterinária , Namíbia/epidemiologia , Conhecimentos, Atitudes e Prática em Saúde , Doenças do Cão/epidemiologia , Doenças do Cão/prevenção & controle , Vacinação/veterinária
4.
Sci Rep ; 13(1): 13743, 2023 08 23.
Artigo em Inglês | MEDLINE | ID: mdl-37612437

RESUMO

This piece of work deals with a time truncated sampling scheme for cancer patients using exponentiated half-logistic distribution (EHLD) based on indeterminacy. We have studied time truncated schemes like repetitive acceptance sampling plan (RASP) under indeterminacy. We have estimated the projected scheme parameters such as sample size and acceptance and rejection sample numbers for known indeterminacy parameters. In addition to the projected sampling scheme quantities, the corresponding tables are generated for various values of indeterminacy parameters. The results of a sampling scheme show that the average sample number (ASN) decreases as indeterminacy values increase. It leads that the indeterminacy parameter is played a crucial portrayal in ASN. A comparative study is carried out with existing sampling schemes based on indeterminacy and classical sampling schemes. The evaluated sampling schemes are exemplified with the help of cancer data. From tables and exemplification, we wind up that the projected RSP scheme under indeterminacy desired a smaller sample size than the existing schemes.


Assuntos
Neoplasias , Humanos , Neoplasias/diagnóstico , Tamanho da Amostra
5.
F1000Res ; 11: 1444, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-38828230

RESUMO

Background: The creation of developing new generalized classes of distributions has attracted applied and theoretical statisticians owing to their properties of flexibility. The development of generalized distribution aims to find distribution flexibility and suitability for available data. In this decade, most authors have developed classes of distributions that are new, to become valuable for applied researchers. Methods: This study aims to develop the odd log-logistic generalized exponential distribution (OLLGED), one of the lifetime newly generated distributions in the field of statistics. The advantage of the newly generated distribution is the heavily tailed distributed lifetime data set. Most of the probabilistic properties are derived including generating functions, moments, and quantile and order statistics. Results: Estimation of the model parameter is done by the maximum likelihood method. The performance of parametric estimation is studied through simulation. Application of OLLGED and its flexibilities is done using two data sets and while its performance is done on the randomly simulated data set. Conclusions: The application and flexibility of the OLLGED are ensured through empirical observation using two sets of lifetime data, establishing that the proposed OLLGED can provide a better fit in comparison to existing rival models, such as odd generalized log-logistic, type-II generalized log-logistic, exponential distributions, odd exponential log-logistic, generalized exponential, and log-logistic.


Assuntos
Modelos Estatísticos , Humanos , Análise de Sobrevida , Neoplasias/tratamento farmacológico , Neoplasias/mortalidade , Funções Verossimilhança , Antineoplásicos/uso terapêutico , Simulação por Computador
6.
PLoS Negl Trop Dis ; 16(8): e0010422, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35994498

RESUMO

Dog-mediated rabies is responsible for tens of thousands of human deaths annually, and in resource-constrained settings, vaccinating dogs to control the disease at source remains challenging. Currently, rabies elimination efforts rely on mass dog vaccination by the parenteral route. To increase the herd immunity, free-roaming and stray dogs need to be specifically addressed in the vaccination campaigns, with oral rabies vaccination (ORV) of dogs being a possible solution. Using a third-generation vaccine and a standardized egg-flavoured bait, bait uptake and vaccination was assessed under field conditions in Namibia. During this trial, both veterinary staff as well as dog owners expressed their appreciation to this approach of vaccination. Of 1,115 dogs offered a bait, 90% (n = 1,006, 95%CI:91-94) consumed the bait and 72.9% (n = 813, 95%CI:70.2-75.4) of dogs were assessed as being vaccinated by direct observation, while for 11.7% (n = 130, 95%CI:9.9-17.7) the status was recorded as "unkown" and 15.4% (n = 172, 95%CI: 13.4-17.7) were considered as being not vaccinated. Smaller dogs and dogs offered a bait with multiple other dogs had significantly higher vaccination rates, while other factors, e.g. sex, confinement status and time had no influence. The favorable results of this first large-scale field trial further support the strategic integration of ORV into dog rabies control programmes. Given the acceptance of the egg-flavored bait under various settings worldwide, ORV of dogs could become a game-changer in countries, where control strategies using parenteral vaccination alone failed to reach sufficient vaccination coverage in the dog population.


Assuntos
Doenças do Cão , Vacina Antirrábica , Raiva , Administração Oral , Animais , Doenças do Cão/epidemiologia , Doenças do Cão/prevenção & controle , Cães , Humanos , Namíbia , Raiva/epidemiologia , Raiva/prevenção & controle , Raiva/veterinária , Vacinação/métodos , Vacinação/veterinária
7.
PLoS Negl Trop Dis ; 14(12): e0008948, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-33370285

RESUMO

Domestic dogs are responsible for 99% of all cases of human rabies and thus, mass dog vaccination has been demonstrated to be the most effective approach towards the elimination of dog-mediated human rabies. Namibia demonstrated the feasibility of this approach by applying government-led strategic rabies vaccination campaigns to reduce both human and dog rabies incidences in the Northern Communal Areas of Namibia since 2016. The lessons learnt using paper-based form for data capturing and management of mass dog vaccination campaign during the pilot and roll out phase of the project (2016-2018) led to the implementation of a simple and accurate data collection tool in the second phase (2019-2022) of the rabies elimination program. In this paper, we describe the implementation of such custom-developed vaccination tracking device, i.e. the Global Alliance for Rabies Control (GARC) Data Logger (GDL), and the integration of the collected data into a website-based rabies surveillance system (Rabies Epidemiological Bulletin-REB) during 2019 and 2020 campaigns. A total of 10,037 dogs and 520 cats were vaccinated during the 2019 campaign and 13,219 dogs and 1,044 cats during the 2020 campaign. The vaccination data were recorded with the GDL and visualized via REB. Subsequent GIS-analysis using gridded population data revealed a suboptimal vaccination coverage in the great majority of grid cells (82%) with a vaccination coverage below 50%. Spatial regression analysis identified the number of schools, estimated human density, and adult dog population were associated with the vaccination performance. However, there was an inverse correlation to human densities. Nonetheless, the use of the GDL improved data capturing and monitoring capacity of the campaign, enabling the Namibian government to improve strategies for the vaccination of at-risk areas towards achieving adequate vaccination coverage which would effectively break the transmission of rabies.


Assuntos
Doenças do Cão/prevenção & controle , Vacinação em Massa/veterinária , Vacina Antirrábica/administração & dosagem , Raiva/prevenção & controle , Cobertura Vacinal/estatística & dados numéricos , Animais , Doenças do Cão/epidemiologia , Cães , Feminino , Masculino , Namíbia/epidemiologia , Raiva/epidemiologia , Raiva/veterinária , Vacinação/estatística & dados numéricos
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