Detalhe da pesquisa
1.
HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.
J Virol
; 92(2)2018 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29118121
2.
No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications.
Arch Virol
; 164(2): 473-482, 2019 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-30415390
3.
Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications.
J Virol
; 91(20)2017 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28768859
4.
HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages.
Retrovirology
; 12: 25, 2015 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25809903
5.
Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes.
Retrovirology
; 12: 48, 2015 Jun 09.
Artigo
Inglês
| MEDLINE | ID: mdl-26055104
6.
A conserved determinant in the V1 loop of HIV-1 modulates the V3 loop to prime low CD4 use and macrophage infection.
J Virol
; 85(5): 2397-405, 2011 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-21159865
7.
Intercompartmental recombination of HIV-1 contributes to env intrahost diversity and modulates viral tropism and sensitivity to entry inhibitors.
J Virol
; 85(12): 6024-37, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21471230
8.
Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes.
J Virol
; 83(6): 2575-83, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19129457
9.
Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors.
Retrovirology
; 5: 5, 2008 Jan 18.
Artigo
Inglês
| MEDLINE | ID: mdl-18205925
10.
Targeted Delivery of Glucan Particle Encapsulated Gallium Nanoparticles Inhibits HIV Growth in Human Macrophages.
J Drug Deliv
; 2016: 8520629, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27965897
11.
Inhibition of CCR5-mediated infection by diverse R5 and R5X4 HIV and SIV isolates using novel small molecule inhibitors of CCR5: effects of viral diversity, target cell and receptor density.
Antiviral Res
; 68(2): 96-108, 2005 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-16157392
12.
Human immunodeficiency viruses: propagation, quantification, and storage.
Curr Protoc Microbiol
; Chapter 15: Unit 15J.1, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23408133
13.
Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis.
Future Virol
; 5(4): 435-451, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20930940
14.
CD4-independent infection of HIV and SIV: implications for envelope conformation and cell tropism in vivo.
AIDS
; 17 Suppl 4: S35-43, 2003.
Artigo
Inglês
| MEDLINE | ID: mdl-15080178
15.
Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia.
J Gen Virol
; 90(Pt 3): 710-722, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19218218
16.
Variation of macrophage tropism among HIV-1 R5 envelopes in brain and other tissues.
J Neuroimmune Pharmacol
; 2(1): 32-41, 2007 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-18040824
17.
Non-macrophage-tropic human immunodeficiency virus type 1 R5 envelopes predominate in blood, lymph nodes, and semen: implications for transmission and pathogenesis.
J Virol
; 80(13): 6324-32, 2006 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-16775320
18.
Human immunodeficiency virus type 1 envelope glycoproteins that lack cytoplasmic domain cysteines: impact on association with membrane lipid rafts and incorporation onto budding virus particles.
J Virol
; 78(10): 5500-6, 2004 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15113929
19.
Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusigenicity for macrophages.
J Virol
; 78(13): 6915-26, 2004 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-15194768