Detalhe da pesquisa
1.
Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21.
Biochem J
; 441(1): 511-22, 2012 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21880012
2.
Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation.
Am J Physiol Regul Integr Comp Physiol
; 298(6): R1560-70, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20357025
3.
The gap junction modifier, GAP-134 [(2S,4R)-1-(2-aminoacetyl)-4-benzamido-pyrrolidine-2-carboxylic acid], improves conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model.
J Pharmacol Exp Ther
; 329(3): 1127-33, 2009 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-19252062
4.
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120.
Peptides
; 30(2): 248-55, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-18992780
5.
GAP-134 ([2S,4R]-1-[2-aminoacetyl]4-benzamidopyrrolidine-2-carboxylic acid) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs.
J Cardiovasc Pharmacol Ther
; 14(3): 207-14, 2009 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19721133
6.
Enhancement of ventricular gap-junction coupling by rotigaptide.
Cardiovasc Res
; 79(3): 416-26, 2008 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18430749
7.
Pharmacological modulation of gap junction function with the novel compound rotigaptide: a promising new principle for prevention of arrhythmias.
Basic Clin Pharmacol Toxicol
; 101(4): 215-30, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17845503
8.
The antiarrhythmic peptide rotigaptide (ZP123) increases gap junction intercellular communication in cardiac myocytes and HeLa cells expressing connexin 43.
Br J Pharmacol
; 147(5): 486-95, 2006 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-16415913
9.
The antiarrhythmic peptide rotigaptide (ZP123) increases connexin 43 protein expression in neonatal rat ventricular cardiomyocytes.
Cell Commun Adhes
; 13(1-2): 21-7, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-16613777
10.
Effects of the new antiarrhythmic peptide ZP123 on epicardial activation and repolarization pattern.
Cell Commun Adhes
; 10(4-6): 371-8, 2003.
Artigo
Inglês
| MEDLINE | ID: mdl-14681044
11.
ZP2307, a novel, cyclic PTH(1-17) analog that augments bone mass in ovariectomized rats.
Bone
; 48(6): 1319-27, 2011 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21376152
12.
Metabolic and cardiac changes in high cholesterol-fructose-fed rats.
J Pharmacol Toxicol Methods
; 61(3): 292-6, 2010.
Artigo
Inglês
| MEDLINE | ID: mdl-20172035
13.
The anti-arrhythmic peptide AAP10 remodels Cx43 and Cx40 expression and function.
Naunyn Schmiedebergs Arch Pharmacol
; 380(1): 11-24, 2009 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19326099
14.
Discovery of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride (GAP-134)13, an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation.
J Med Chem
; 52(4): 908-11, 2009 Feb 26.
Artigo
Inglês
| MEDLINE | ID: mdl-19175320
15.
Differential down-regulation of aquaporin-2 in rat kidney zones by peripheral nociceptin/orphanin FQ receptor agonism and vasopressin type-2 receptor antagonism.
J Pharmacol Exp Ther
; 323(2): 516-24, 2007 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-17693587
16.
Pharmacological stimulation of cardiac gap junction coupling does not affect ischemia-induced focal ventricular tachycardia or triggered activity in dogs.
Am J Physiol Heart Circ Physiol
; 288(2): H511-6, 2005 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-15650154
17.
ZP123 increases gap junctional conductance and prevents reentrant ventricular tachycardia during myocardial ischemia in open chest dogs.
J Cardiovasc Electrophysiol
; 14(5): 510-20, 2003 May.
Artigo
Inglês
| MEDLINE | ID: mdl-12776869
18.
Opioid receptor-like 1 stimulation in the collecting duct induces aquaresis through vasopressin-independent aquaporin-2 downregulation.
Am J Physiol Renal Physiol
; 287(1): F160-8, 2004 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-15010357