Detalhe da pesquisa
1.
Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly.
Nature
; 619(7970): 555-562, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-37380776
2.
Mechanism-based traps enable protease and hydrolase substrate discovery.
Nature
; 602(7898): 701-707, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35173328
3.
Translational enhancement by base editing of the Kozak sequence rescues haploinsufficiency.
Nucleic Acids Res
; 50(18): 10756-10771, 2022 10 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36165847
4.
Thermally Driven Membrane Phase Transitions Enable Content Reshuffling in Primitive Cells.
J Am Chem Soc
; 143(40): 16589-16598, 2021 10 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34597506
5.
The VCP/p97 and YOD1 Proteins Have Different Substrate-dependent Activities in Endoplasmic Reticulum-associated Degradation (ERAD).
J Biol Chem
; 290(47): 28175-28188, 2015 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-26463207
6.
CD4 and BST-2/tetherin proteins retro-translocate from endoplasmic reticulum to cytosol as partially folded and multimeric molecules.
J Biol Chem
; 289(1): 1-12, 2014 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24257748
7.
Piezoelectric energy harvesting solutions.
Sensors (Basel)
; 14(3): 4755-90, 2014 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24618725
8.
Selective targeting of proteins within secretory pathway for endoplasmic reticulum-associated degradation.
J Biol Chem
; 287(24): 20007-15, 2012 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-22523070
9.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Nat Commun
; 14(1): 603, 2023 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36746939
10.
Refactored genetic codes enable bidirectional genetic isolation.
Science
; 378(6619): 516-523, 2022 Nov 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36264827
11.
Synthetic genomics for curing genetic diseases.
Prog Mol Biol Transl Sci
; 182: 477-520, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34175051
12.
Pharmacological inactivation of the prion protein by targeting a folding intermediate.
Commun Biol
; 4(1): 62, 2021 01 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33437023
13.
Author Correction: Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing.
Nat Commun
; 11(1): 5457, 2020 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33093446
14.
CRISPR-Csy4-Mediated Editing of Rotavirus Double-Stranded RNA Genome.
Cell Rep
; 32(13): 108205, 2020 09 29.
Artigo
Inglês
| MEDLINE | ID: mdl-32997981
15.
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors.
Cell Death Dis
; 11(12): 1039, 2020 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33288740
16.
BiP/GRP78 Mediates ERAD Targeting of Proteins Produced by Membrane-Bound Ribosomes Stalled at the STOP-Codon.
J Mol Biol
; 431(2): 123-141, 2019 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30367842
17.
Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing.
Nat Commun
; 10(1): 3556, 2019 08 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31391465
18.
VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9.
Mol Ther Nucleic Acids
; 12: 453-462, 2018 Sep 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30195783
19.
A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Nat Biotechnol
; 36(3): 265-271, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29431739
20.
Hit and go CAS9 delivered through a lentiviral based self-limiting circuit.
Nat Commun
; 8: 15334, 2017 05 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28530235