Detalhe da pesquisa
1.
Born equal: dual safeguards for daughter cell size symmetry.
Cell
; 154(2): 269-71, 2013 Jul 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23870117
2.
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.
Nat Chem Biol
; 15(8): 822-829, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31285596
3.
Tumor clonality and resistance mechanisms in EGFR mutation-positive non-small-cell lung cancer: implications for therapeutic sequencing.
Future Oncol
; 15(6): 637-652, 2019 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-30404555
4.
Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion.
EMBO J
; 33(22): 2623-42, 2014 Nov 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25257310
5.
Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis.
Nature
; 492(7428): 276-9, 2012 Dec 13.
Artigo
Inglês
| MEDLINE | ID: mdl-23235882
6.
Discovery of a Novel Potent EGFR Inhibitor Against EGFR Activating Mutations and On-Target Resistance in NSCLC.
Clin Cancer Res
; 30(8): 1582-1594, 2024 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38330145
7.
Combined KRASG12C and SOS1 inhibition enhances and extends the anti-tumor response in KRASG12C-driven cancers by addressing intrinsic and acquired resistance.
bioRxiv
; 2023 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36747713
8.
Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle.
Dev Cell
; 12(5): 713-25, 2007 May.
Artigo
Inglês
| MEDLINE | ID: mdl-17488623
9.
Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells.
J Cell Sci
; 123(Pt 9): 1395-400, 2010 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20356927
10.
Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation.
PLoS Biol
; 7(5): e1000110, 2009 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-19468300
11.
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.
Nature
; 441(7089): 53-61, 2006 May 04.
Artigo
Inglês
| MEDLINE | ID: mdl-16541024
12.
Expanding the Reach of Precision Oncology by Drugging All KRAS Mutants.
Cancer Discov
; 12(4): 924-937, 2022 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35046095
13.
Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling.
Nat Cancer
; 3(7): 821-836, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35883003
14.
Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers.
Life Sci Alliance
; 4(1)2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33199508
15.
Acute BAF perturbation causes immediate changes in chromatin accessibility.
Nat Genet
; 53(3): 269-278, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33558760
16.
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition.
Cancer Discov
; 11(1): 142-157, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32816843
17.
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.
Curr Biol
; 17(4): 316-22, 2007 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-17291758
18.
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.
Curr Biol
; 17(4): 304-15, 2007 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-17291761
19.
The 'anaphase problem': how to disable the mitotic checkpoint when sisters split.
Biochem Soc Trans
; 38(6): 1660-6, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21118144
20.
Cell Division: Switching On ECT2 in a Non-Canonical Fashion.
Curr Biol
; 30(16): R947-R949, 2020 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32810457