Detalhe da pesquisa
1.
Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming.
Pharmacol Res
; 179: 106193, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35358682
2.
Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women.
Diabetologia
; 64(12): 2817-2828, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34510226
3.
Postexercise changes in myocellular lipid droplet characteristics of young lean individuals are affected by circulatory nonesterified fatty acids.
Am J Physiol Endocrinol Metab
; 321(4): E453-E463, 2021 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34396784
4.
The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity.
Int J Obes (Lond)
; 45(7): 1510-1520, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33935282
5.
Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle.
Proc Natl Acad Sci U S A
; 115(30): 7789-7794, 2018 07 24.
Artigo
Inglês
| MEDLINE | ID: mdl-29987027
6.
One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study with unilateral limb suspension.
Diabetologia
; 63(6): 1211-1222, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32185462
7.
Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans.
Proc Natl Acad Sci U S A
; 111(26): 9597-602, 2014 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24979806
8.
ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity.
Diabetologia
; 59(5): 1030-9, 2016 May.
Artigo
Inglês
| MEDLINE | ID: mdl-26886198
9.
Reduction of non-esterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial.
Diabetologia
; 57(3): 572-81, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24310562
10.
PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans.
J Lipid Res
; 54(2): 522-34, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23175776
11.
Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trial.
Metabolism
; 140: 155396, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36592688
12.
Cotadutide promotes glycogenolysis in people with overweight or obesity diagnosed with type 2 diabetes.
Nat Metab
; 5(12): 2086-2093, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38066113
13.
The tissue-specific metabolic effects of the PPARα agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study.
Obesity (Silver Spring)
; 31(10): 2493-2504, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37670579
14.
Enhanced lipid-but not carbohydrate-supported mitochondrial respiration in skeletal muscle of PGC-1α overexpressing mice.
J Cell Physiol
; 227(3): 1026-33, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-21520076
15.
Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes.
Nutr Diabetes
; 12(1): 35, 2022 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35931683
16.
A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes.
Nat Commun
; 13(1): 3508, 2022 06 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35717342
17.
Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism.
Mol Metab
; 66: 101620, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36280113
18.
Mitochondrial function and insulin resistance during aging: a mini-review.
Gerontology
; 57(5): 387-96, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-20798481
19.
Elevated Plasma Branched-Chain Amino Acid Levels Correlate With Type 2 Diabetes-Related Metabolic Disturbances.
J Clin Endocrinol Metab
; 106(4): e1827-e1836, 2021 03 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33079174
20.
Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial.
Diabetes Care
; 44(6): 1334-1343, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33858855