Detalhe da pesquisa
1.
Development of an intracellular quantitative assay to measure compound binding kinetics.
Cell Chem Biol
; 29(2): 287-299.e8, 2022 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34520747
2.
Reducing False Positives through the Application of Fluorescence Lifetime Technology: A Comparative Study Using TYK2 Kinase as a Model System.
SLAS Discov
; 26(5): 663-675, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33783261
3.
Optimization of a Series of 2,3-Dihydrobenzofurans as Highly Potent, Second Bromodomain (BD2)-Selective, Bromo and Extra-Terminal Domain (BET) Inhibitors.
J Med Chem
; 64(15): 10711-10741, 2021 08 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34260229
4.
Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors.
J Med Chem
; 64(6): 3249-3281, 2021 03 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33662213
5.
Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding Mode.
J Med Chem
; 63(10): 5212-5241, 2020 05 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32321240
6.
Cellular Target Engagement Approaches to Monitor Epigenetic Reader Domain Interactions.
SLAS Discov
; 25(2): 163-175, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31875412
7.
Development of an intracellular quantitative assay to measure compound binding kinetics.
Cell Chem Biol
; 30(12): 1692, 2023 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38134882