Detalhe da pesquisa
1.
Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition.
Mol Psychiatry
; 28(2): 668-697, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36385166
2.
New Insights into the Mechanism of NO3- Selectivity in the Human Kidney Chloride Channel ClC-Ka and the CLC Protein Family.
J Am Soc Nephrol
; 30(2): 293-302, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30635372
3.
Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels.
Proc Natl Acad Sci U S A
; 110(48): 19354-9, 2013 Nov 26.
Artigo
Inglês
| MEDLINE | ID: mdl-24167264
4.
Vesicular CLC chloride/proton exchangers in health and diseases.
Front Pharmacol
; 14: 1295068, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-38027030
5.
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.
J Neurosci
; 31(28): 10412-23, 2011 Jul 13.
Artigo
Inglês
| MEDLINE | ID: mdl-21753018
6.
CLC channels and transporters: proteins with borderline personalities.
Biochim Biophys Acta
; 1798(8): 1457-64, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20188062
7.
Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.
Nature
; 436(7049): 420-3, 2005 Jul 21.
Artigo
Inglês
| MEDLINE | ID: mdl-16034421
8.
Molecular switch for CLC-K Cl- channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.
Proc Natl Acad Sci U S A
; 105(4): 1369-73, 2008 Jan 29.
Artigo
Inglês
| MEDLINE | ID: mdl-18216243
9.
Pathobiologic Mechanisms of Neurodegeneration in Osteopetrosis Derived From Structural and Functional Analysis of 14 ClC-7 Mutants.
J Bone Miner Res
; 36(3): 531-545, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33125761
10.
TMEM16 proteins: unknown structure and confusing functions.
J Mol Biol
; 427(1): 94-105, 2015 Jan 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25451786
11.
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1.
Br J Pharmacol
; 139(7): 1255-64, 2003 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-12890704
12.
Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.
Nat Struct Mol Biol
; 21(5): 456-63, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24747941
13.
Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.
Nat Commun
; 4: 2367, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23996062
14.
Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.
Nat Struct Mol Biol
; 19(5): 525-31, S1, 2012 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-22484316
15.
Proton block of the CLC-5 Cl-/H+ exchanger.
J Gen Physiol
; 135(6): 653-9, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20513761
16.
A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.
J Gen Physiol
; 136(3): 311-23, 2010 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-20805576
17.
Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.
Nat Struct Mol Biol
; 16(12): 1294-301, 2009 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-19898476
18.
Mechanism of interaction of niflumic acid with heterologously expressed kidney CLC-K chloride channels.
J Membr Biol
; 216(2-3): 73-82, 2007 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-17659402
19.
Activation and inhibition of kidney CLC-K chloride channels by fenamates.
Mol Pharmacol
; 69(1): 165-73, 2006 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-16244177
20.
Tonic and phasic guanidinium toxin-block of skeletal muscle Na channels expressed in Mammalian cells.
Biophys J
; 84(5): 2999-3006, 2003 May.
Artigo
Inglês
| MEDLINE | ID: mdl-12719231