Detalhe da pesquisa
1.
In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir.
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29084747
2.
Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach.
Bioorg Med Chem Lett
; 28(10): 1708-1713, 2018 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29691138
3.
In vitro and in vivo antiviral activity and resistance profile of the hepatitis C virus NS3/4A protease inhibitor ABT-450.
Antimicrob Agents Chemother
; 59(2): 988-97, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25451053
4.
Identification and characterization of mutations conferring resistance to an HCV RNA-dependent RNA polymerase inhibitor in vitro.
Antiviral Res
; 76(1): 93-7, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17561278
5.
A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations.
J Virol Methods
; 145(2): 137-45, 2007 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-17604129
6.
Use of SAM2 biotin capture membrane in microarrayed compound screening (muARCS) format for nucleic acid polymerization assays.
J Biomol Screen
; 8(3): 273-82, 2003 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-12857381
7.
Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology.
Hepatology
; 45(6): 1413-21, 2007 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-17518369
8.
Mechanistic study of HCV polymerase inhibitors at individual steps of the polymerization reaction.
Biochemistry
; 45(38): 11312-23, 2006 Sep 26.
Artigo
Inglês
| MEDLINE | ID: mdl-16981691
9.
Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro.
Antimicrob Agents Chemother
; 49(10): 4305-14, 2005 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16189112
10.
Complementation in cells cotransfected with a mixture of wild-type and mutant human immunodeficiency virus (HIV) influences the replication capacities and phenotypes of mutant variants in a single-cycle HIV resistance assay.
J Clin Microbiol
; 42(9): 4169-74, 2004 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-15365007
11.
Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro.
Antimicrob Agents Chemother
; 48(6): 2260-6, 2004 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-15155230