Detalhe da pesquisa
1.
Structural architecture of the human NALCN channelosome.
Nature
; 603(7899): 180-186, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34929720
2.
Structure of the human sodium leak channel NALCN.
Nature
; 587(7833): 313-318, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32698188
3.
Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5.
Proc Natl Acad Sci U S A
; 118(33)2021 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34373326
4.
Evolutionarily Conserved Interactions within the Pore Domain of Acid-Sensing Ion Channels.
Biophys J
; 118(4): 861-872, 2020 02 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31630811
5.
Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore module.
bioRxiv
; 2024 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38328210
6.
Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels.
Cell Chem Biol
; 2023 Dec 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38113885
7.
P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity.
Br J Pharmacol
; 179(14): 3859-3874, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35285517
8.
Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel.
Nat Commun
; 13(1): 1416, 2022 03 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35301303
9.
Ion channel engineering using protein trans-splicing.
Methods Enzymol
; 654: 19-48, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34120713
10.
Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction.
J Med Chem
; 63(22): 13709-13718, 2020 11 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33143415
11.
High-Sensitivity Fluorometry to Resolve Ion Channel Conformational Dynamics.
Cell Rep
; 22(6): 1615-1626, 2018 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29425514