Detalhe da pesquisa
1.
Severe Immune-Related Enteritis after In Utero Exposure to Pembrolizumab.
N Engl J Med
; 389(19): 1790-1796, 2023 Nov 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37937778
2.
WEE1 inhibitor adavosertib in combination with carboplatin in advanced TP53 mutated ovarian cancer: A biomarker-enriched phase II study.
Gynecol Oncol
; 174: 239-246, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37236033
3.
A Phase I dose-escalation study of two cycles carboplatin-olaparib followed by olaparib monotherapy in patients with advanced cancer.
Int J Cancer
; 148(12): 3041-3050, 2021 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33539540
4.
Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir.
Pharmacogenomics J
; 21(3): 336-345, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33649517
5.
Dihydrofolate Reductase/Thymidylate Synthase Fine-Tunes the Folate Status and Controls Redox Homeostasis in Plants.
Plant Cell
; 29(11): 2831-2853, 2017 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-28939595
6.
Phase I pharmacological study of continuous chronomodulated capecitabine treatment.
Pharm Res
; 37(5): 89, 2020 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32382808
7.
Multiparameter Flow Cytometry Assay for Quantification of Immune Cell Subsets, PD-1 Expression Levels and PD-1 Receptor Occupancy by Nivolumab and Pembrolizumab.
Cytometry A
; 95(10): 1053-1065, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31407460
8.
EpCAM-based assays for epithelial tumor cell detection in cerebrospinal fluid.
J Neurooncol
; 137(1): 1-10, 2018 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-29192390
9.
Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
Br J Clin Pharmacol
; 84(12): 2761-2769, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30047584
10.
Increased risk of severe fluoropyrimidine-associated toxicity in patients carrying a G to C substitution in the first 28-bp tandem repeat of the thymidylate synthase 2R allele.
Int J Cancer
; 138(1): 245-53, 2016 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26189437
11.
Bevacizumab combined with docetaxel, oxaliplatin, and capecitabine, followed by maintenance with capecitabine and bevacizumab, as first-line treatment of patients with advanced HER2-negative gastric cancer: A multicenter phase 2 study.
Cancer
; 122(9): 1434-43, 2016 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26970343
12.
Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers.
Br J Clin Pharmacol
; 82(3): 706-16, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27161955
13.
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.
Invest New Drugs
; 33(1): 201-14, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25344453
14.
"Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183".
Invest New Drugs
; 32(6): 1083-95, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25078948
15.
ELISA assay for the quantification of ipilimumab in human serum, plasma, milk, and cerebrospinal fluid.
J Pharm Biomed Anal
; 245: 116140, 2024 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38701533
16.
Is Higher Docetaxel Clearance in Prostate Cancer Patients Explained by Higher CYP3A? An In Vivo Phenotyping Study with Midazolam.
J Clin Pharmacol
; 64(2): 155-163, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-37789682
17.
Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA.
Invest New Drugs
; 31(5): 1125-35, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23315030
18.
Pharmacodynamic assay of thymidylate synthase activity in peripheral blood mononuclear cells.
Anal Bioanal Chem
; 405(8): 2495-503, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23314484
19.
Correction of peripheral blood mononuclear cell cytosolic protein for hemoglobin contamination.
Anal Bioanal Chem
; 405(7): 2391-5, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23318760
20.
High accumulation of nivolumab in human breast milk: A case report.
Biomed Pharmacother
; 166: 115354, 2023 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-37625324