Detalhe da pesquisa
1.
Synthesis of Pharmaceutically Relevant Arylamines Enabled by a Nitroreductase from Bacillus tequilensis.
Chembiochem
; 25(10): e202300846, 2024 May 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38502784
2.
Multigram-scale chemoenzymatic synthesis of diverse aminopolycarboxylic acids as potential metallo-ß-lactamase inhibitors.
Org Biomol Chem
; 22(3): 491-495, 2024 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38126753
3.
SLC1A3 contributes to L-asparaginase resistance in solid tumors.
EMBO J
; 38(21): e102147, 2019 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31523835
4.
Biocatalytic Cascade Synthesis of Enantioenriched Epoxides and Triols from Biomass-Derived Synthons Driven by Specifically Designed Enzymes.
Chemistry
; 29(31): e202300697, 2023 Jun 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36893219
5.
Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury.
Cell Mol Life Sci
; 79(2): 105, 2022 Jan 29.
Artigo
Inglês
| MEDLINE | ID: mdl-35091838
6.
Enzymatic Oxy- and Amino-Functionalization in Biocatalytic Cascade Synthesis: Recent Advances and Future Perspectives.
Angew Chem Int Ed Engl
; 62(48): e202309012, 2023 11 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37639631
7.
Enantiocomplementary Michael Additions of Acetaldehyde to Aliphatic Nitroalkenes Catalyzed by Proline-Based Carboligases.
Chembiochem
; 23(6): e202100644, 2022 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35049100
8.
Enhancing the Peroxygenase Activity of a Cofactor-Independent Peroxyzyme by Directed Evolution Enabling Gram-Scale Epoxide Synthesis.
Chemistry
; 28(59): e202201651, 2022 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-35861144
9.
4-Iodopyrimidine Labeling Reveals Nuclear Translocation and Nuclease Activity for Both MIF and MIF2.
Chemistry
; 28(1): e202103030, 2022 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34724273
10.
Unlocking New Reactivities in Enzymes by Iminium Catalysis.
Angew Chem Int Ed Engl
; 61(30): e202203613, 2022 07 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35524737
11.
Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C-C Bond-Forming Enzyme.
Angew Chem Int Ed Engl
; 61(8): e202113970, 2022 02 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34890491
12.
Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue.
J Am Chem Soc
; 143(3): 1513-1520, 2021 01 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33449695
13.
Using Mutability Landscapes To Guide Enzyme Thermostabilization.
Chembiochem
; 22(1): 170-175, 2021 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32790123
14.
The broad amine scope of pantothenate synthetase enables the synthesis of pharmaceutically relevant amides.
Org Biomol Chem
; 19(20): 4515-4519, 2021 05 26.
Artigo
Inglês
| MEDLINE | ID: mdl-33913984
15.
Biocatalytic enantioselective hydroaminations enabling synthesis of N-arylalkyl-substituted L-aspartic acids.
Org Biomol Chem
; 19(29): 6407-6411, 2021 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34235532
16.
Biocatalytic Asymmetric Cyclopropanations via Enzyme-Bound Iminium Ion Intermediates.
Angew Chem Int Ed Engl
; 60(45): 24059-24063, 2021 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34490955
17.
Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells.
Angew Chem Int Ed Engl
; 60(32): 17514-17521, 2021 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34018657
18.
The role of MIF in chronic lung diseases: looking beyond inflammation.
Am J Physiol Lung Cell Mol Physiol
; 318(6): L1183-L1197, 2020 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32208924
19.
In Situ Acetaldehyde Synthesis for Carboligation Reactions.
Chembiochem
; 21(10): 1505-1509, 2020 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31868962
20.
Recent Applications of Carbon-Nitrogen Lyases in Asymmetric Synthesis of Noncanonical Amino Acids and Heterocyclic Compounds.
Chembiochem
; 21(19): 2733-2742, 2020 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32315503