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1.
Opt Express ; 31(9): 15045-15057, 2023 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-37157355

RESUMO

The performance of modular, networked quantum technologies will be strongly dependent upon the quality of their quantum light-matter interconnects. Solid-state colour centres, and in particular T centres in silicon, offer competitive technological and commercial advantages as the basis for quantum networking technologies and distributed quantum computing. These newly rediscovered silicon defects offer direct telecommunications-band photonic emission, long-lived electron and nuclear spin qubits, and proven native integration into industry-standard, CMOS-compatible, silicon-on-insulator (SOI) photonic chips at scale. Here we demonstrate further levels of integration by characterizing T centre spin ensembles in single-mode waveguides in SOI. In addition to measuring long spin T1 times, we report on the integrated centres' optical properties. We find that the narrow homogeneous linewidth of these waveguide-integrated emitters is already sufficiently low to predict the future success of remote spin-entangling protocols with only modest cavity Purcell enhancements. We show that further improvements may still be possible by measuring nearly lifetime-limited homogeneous linewidths in isotopically pure bulk crystals. In each case the measured linewidths are more than an order of magnitude lower than previously reported and further support the view that high-performance, large-scale distributed quantum technologies based upon T centres in silicon may be attainable in the near term.

2.
Phys Rev Lett ; 113(26): 267604, 2014 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-25615386

RESUMO

We experimentally demonstrate the first inductive readout of optically hyperpolarized phosphorus-31 donor nuclear spins in an isotopically enriched silicon-28 crystal. The concentration of phosphorus donors in the crystal was 1.5×10(15) cm(-3), 3 orders of magnitude lower than has previously been detected via direct inductive detection. The signal-to-noise ratio measured in a single free induction decay from a 1 cm(3) sample (≈10(15) spins) was 113. By transferring the sample to an X-band ESR spectrometer, we were able to obtain a lower bound for the nuclear spin polarization at 1.7 K of ∼64%. The (31)P-T2 measured with a Hahn echo sequence was 420 ms at 1.7 K, which was extended to 1.2 s with a Carr Purcell cycle. The T1 of the (31)P nuclear spins at 1.7 K is extremely long and could not be determined, as no decay was observed even on a time scale of 4.5 h. Optical excitation was performed with a 1047 nm laser, which provided above-band-gap excitation of the silicon. The buildup of the hyperpolarization at 4.2 K followed a single exponential with a characteristic time of 577 s, while the buildup at 1.7 K showed biexponential behavior with characteristic time constants of 578 and 5670 s.

3.
HNO ; 58(9): 931-3, 2010 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-20464358

RESUMO

Urbach-Wiethe syndrome (hyalinosis cutis et mucosae) is an autosomal-recessive inherited disease. It often presents with typical symptoms such as skin lesions (especially in the face and neck area), dyspnea, and maldigestion. Hoarseness is a leading symptom in young children. These manifestations are caused by the assimilation of glycoproteins in mesenchymal tissue. Our case report shows that hoarseness does not necessarily appear only in children, but can also appear later. Furthermore, the assimilation of glycoproteins in the supraglottic area may also cause dysphonia. Due to the varied features of this disease, interdisciplinary check-ups are necessary at regular intervals.


Assuntos
Disfonia/diagnóstico , Epiglote/patologia , Neoplasias Laríngeas/diagnóstico , Proteinose Lipoide de Urbach e Wiethe/complicações , Proteinose Lipoide de Urbach e Wiethe/diagnóstico , Pneumonia/diagnóstico , Humanos , Pressão , Recidiva
4.
Rofo ; 145(6): 651-6, 1986 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-3025950

RESUMO

Eleven patients with known malignant tumours of the outer ear and three patients with otitis externa maligna were examined by high resolution CT. CT provided accurate information concerning soft tissue infiltration into the parotid or subtemporal tissues, and of the bony destruction in the mastoid, meatus and tympanic cavity. Absolute differentiation between a malignant tumour and otitis cisterna maligna is not possible, not even by high resolution CT.


Assuntos
Carcinoma Adenoide Cístico/diagnóstico por imagem , Carcinoma Basocelular/diagnóstico por imagem , Carcinoma de Células Escamosas/diagnóstico por imagem , Neoplasias da Orelha/diagnóstico por imagem , Orelha Externa , Tomografia Computadorizada por Raios X , Carcinoma Adenoide Cístico/patologia , Carcinoma Basocelular/patologia , Carcinoma de Células Escamosas/patologia , Diagnóstico Diferencial , Meato Acústico Externo/diagnóstico por imagem , Meato Acústico Externo/patologia , Neoplasias da Orelha/patologia , Orelha Média/diagnóstico por imagem , Orelha Média/patologia , Humanos , Processo Mastoide/diagnóstico por imagem , Processo Mastoide/patologia , Invasividade Neoplásica , Otite Externa/diagnóstico , Neoplasias Cranianas/diagnóstico por imagem , Neoplasias Cranianas/patologia , Tomografia Computadorizada por Raios X/métodos
5.
Rofo ; 143(3): 322-6, 1985 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-2996071

RESUMO

In thirty patients with cholesteatomas of the middle ear, high resolution CT of the petrous bone was performed in conjunction with the clinical examination. The extent of the soft tissue process can be demonstrated by CT, but differentiation of the cholesteatoma from the accompanying inflammatory changes is not possible. Typical complications such as destruction of the auditory ossicles, the bony labyrinth, the facial canal, the lateral wall of the attic and the superior and inferior walls of the tympanic cavity are clearly demonstrated. Changes in the mastoids are better demonstrated than by conventional radiography. Using the high contrast and special resolution of modern high resolution CT, this has become the method of choice in the investigation of cholesteatomas of the middle ear.


Assuntos
Colesteatoma/diagnóstico por imagem , Orelha Média/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Otopatias/diagnóstico por imagem , Ossículos da Orelha/diagnóstico por imagem , Humanos , Osso Petroso/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos
6.
Rofo ; 146(1): 7-13, 1987 Jan.
Artigo em Alemão | MEDLINE | ID: mdl-3027791

RESUMO

High resolution computer tomographic examinations of the petrous bones were performed on 19 patients with confirmed peripheral facial nerve paralysis. High resolution CT provides accurate information regarding the extent, and usually regarding the type, of pathological process; this can be accurately localised with a view to possible surgical treatment. The examination also differentiates this from idiopathic paresis, which showed no radiological changes. Destruction of the petrous bone, without facial nerve symptoms, makes early suitable treatment mandatory.


Assuntos
Paralisia Facial/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Paralisia Facial/etiologia , Humanos , Osso Petroso/diagnóstico por imagem
7.
Rofo ; 147(1): 39-45, 1987 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-3039599

RESUMO

Twenty-one patients with congenital deformities of the petrous bones were examined by high resolution computed tomography. This allows an accurate description of the extent of the malformation in all parts of the cochlear and vestibular organs; only localised changes in the auditory ossicles, such as fixation of the stapes and changes in the soft tissue portions of the labyrinth, cannot be shown. Improved demonstration of soft tissues while using less radiation makes high resolution CT preferable to conventional polytomography. It is also easier to perform and provides axial projections which are essential for the elucidation of malformations of the middle and inner ear.


Assuntos
Cóclea/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Vestíbulo do Labirinto/diagnóstico por imagem , Audiometria , Cóclea/anormalidades , Humanos , Osso Petroso/anormalidades , Osso Petroso/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Vestíbulo do Labirinto/anormalidades
8.
Rofo ; 151(6): 653-8, 1989 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-2556738

RESUMO

The pre-operative laryngoscopic and CT findings in the larynx in 50 patients with malignant laryngeal tumours were compared. Laryngoscopy showed an accuracy for T-staging of 78.6% and CT an accuracy of 80%. In addition, CT complemented the endoscopic findings by demonstrating the depth of tumour invasion. The changes in individual anatomical portions of the larynx were compared, using both methods. CT and palpation showed equal specificity for lymph node staging, but CT is markedly superior in sensitivity.


Assuntos
Neoplasias Laríngeas/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adulto , Idoso , Carcinoma de Células Escamosas/diagnóstico por imagem , Carcinoma de Células Escamosas/patologia , Feminino , Humanos , Neoplasias Laríngeas/patologia , Laringoscopia , Masculino , Pessoa de Meia-Idade
9.
Rofo ; 152(6): 644-8, 1990 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-2163067

RESUMO

High-resolution CT of the petrous bone was carried out in 259 patients with clinically diagnosed abnormalities of the inner ear; in some the lesions were bilateral. In 62 patients (approximately 20%), the scans showed findings which related to the signs and symptoms. Patients with hearing loss and vestibular neuronitis showed no abnormalities. Amongst the remaining patients, the most common findings were acoustic neuromas (17 cases), cochlear otospongiosis (14 cases), malformations (13 cases) and tumours or cholesteatomas of the labyrinth (13 cases) as well as single rare isolated lesions.


Assuntos
Orelha Interna/diagnóstico por imagem , Doenças do Labirinto/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Doenças Cocleares/diagnóstico por imagem , Diagnóstico Diferencial , Transtornos da Audição/diagnóstico por imagem , Humanos , Osso Petroso/diagnóstico por imagem
10.
Rofo ; 146(3): 273-7, 1987 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-3031756

RESUMO

The place of MRT, using surface coils, has been evaluated retrospectively in 27 patients with clinically confirmed malignant tumours of the mouth and pharynx. The extent of the tumour and its relationship to neighbouring structures is well demonstrated. The resolution obtainable by using surface coils is almost as good as that of CT. Soft tissue contrast is better in showing the spread and size of the tumour. A disadvantage of MRT is the inability in most cases to demonstrate bone destruction. Differentiation between residual tumour, recurrence and scarring is possible only occasionally. Quantitative MRT may be expected to lead to improved diagnosis during the course of following up.


Assuntos
Espectroscopia de Ressonância Magnética , Neoplasias Bucais/diagnóstico , Neoplasias Faríngeas/diagnóstico , Humanos , Espectroscopia de Ressonância Magnética/instrumentação , Neoplasias Bucais/patologia , Recidiva Local de Neoplasia/diagnóstico , Recidiva Local de Neoplasia/patologia , Estadiamento de Neoplasias , Neoplasias Faríngeas/patologia , Cuidados Pré-Operatórios , Estudos Retrospectivos
11.
Int J Pediatr Otorhinolaryngol ; 34(1-2): 159-64, 1996 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-8770684

RESUMO

We report on a 2-year-9-month-old boy with the typical features of craniometaphyseal dysplasia with hyperostosis and sclerosis of the cranial vault and mild splaying of the metaphyses. The boy already presented during the neonatal period with the unusual clinical picture of breathing and feeding problems due to severely enlarged and ossified inferior nasal conchae causing obstruction of the nasal lumen.


Assuntos
Doenças do Desenvolvimento Ósseo/diagnóstico , Obstrução Nasal/congênito , Idade de Início , Doenças do Desenvolvimento Ósseo/complicações , Doenças do Desenvolvimento Ósseo/diagnóstico por imagem , Pré-Escolar , Diagnóstico Diferencial , Face/diagnóstico por imagem , Face/patologia , Insuficiência de Crescimento/etiologia , Humanos , Masculino , Obstrução Nasal/diagnóstico , Obstrução Nasal/etiologia , Radiografia , Insuficiência Respiratória/etiologia , Crânio/diagnóstico por imagem , Crânio/patologia
12.
Science ; 336(6086): 1280-3, 2012 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-22679091

RESUMO

A quantum computer requires systems that are isolated from their environment, but can be integrated into devices, and whose states can be measured with high accuracy. Nuclear spins in solids promise long coherence lifetimes, but they are difficult to initialize into known states and to detect with high sensitivity. We show how the distinctive optical properties of enriched (28)Si enable the use of hyperfine-resolved optical transitions, as previously applied to great effect for isolated atoms and ions in vacuum. Together with efficient Auger photoionization, these resolved hyperfine transitions permit rapid nuclear hyperpolarization and electrical spin-readout. We combine these techniques to detect nuclear magnetic resonance from dilute (31)P in the purest available sample of (28)Si, at concentrations inaccessible to conventional measurements, measuring a solid-state coherence time of over 180 seconds.

13.
Phys Rev Lett ; 102(25): 257401, 2009 Jun 26.
Artigo em Inglês | MEDLINE | ID: mdl-19659118

RESUMO

We demonstrate a method which can hyperpolarize both the electron and nuclear spins of 31P donors in Si at low field, where both would be essentially unpolarized in equilibrium. It is based on the selective ionization of donors in a specific hyperfine state by optically pumping donor bound exciton hyperfine transitions, which can be spectrally resolved in 28Si. Electron and nuclear polarizations of 90% and 76%, respectively, are obtained in less than a second, providing an initialization mechanism for qubits based on these spins, and enabling further ESR and NMR studies on dilute 31P in 28Si.

14.
Phys Rev Lett ; 100(17): 177402, 2008 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-18518336

RESUMO

Dramatic reductions of the linewidths of well-known deep centers in 28Si reveal "isotopic fingerprints" of the constituents. The approximately 1014 meV Cu center, thought to be either a Cu pair or an isolated Cu, is shown to contain four Cu atoms, and the approximately 780 meV Ag center is shown to contain four Ag. The approximately 944 meV ;{*}Cu center, thought to be a different configuration of a Cu pair, in fact contains three Cu and one Ag, and a new two-Cu two-Ag center is found. The approximately 735 meV center, previously assigned to Fe, actually contains Au and three Cu. This suggests a family of four-atom (Cu, Ag, Au) centers.

15.
Phys Rev Lett ; 97(22): 227401, 2006 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-17155840

RESUMO

We resolve the remarkably sharp bound exciton transitions of highly enriched 28Si using a single-frequency laser and photoluminescence excitation spectroscopy, as well as photocurrent spectroscopy. Well-resolved doublets in the spectrum of the 31P donor reflect the hyperfine coupling of the electronic and nuclear donor spins. The optical detection of the nuclear spin state, and selective pumping and ionization of donors in specific electronic and nuclear spin states, suggests a number of new possibilities which could be useful for the realization of silicon-based quantum computers.

17.
Laryngol Rhinol Otol (Stuttg) ; 58(7): 616-21, 1979 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-481041

RESUMO

The subject of this analysis are the results of treatment of sinusitis in its varying forms and degrees with the "Climate Mask 500" in conjunction with antrum puncture. Either dry or humit warm-air inhalations with coniferous oil additives were prescribed depending on the type of sillness. In 100% of the cases so treated normalisation or improvement of the subjective complaint could be observed. The objective findings normalised or improved in 80% of the cases. Because of its therapeutic value, its simplicity, the reduction in medication and the lack of side effects, inhalation treatment with the "Climate Mask 500" can be said to be a useful aid in a causal therapy of sinusitis.


Assuntos
Terapia Respiratória/instrumentação , Sinusite/terapia , Adulto , Estudos de Avaliação como Assunto , Humanos , Masculino , Máscaras , Pessoa de Meia-Idade
18.
Laryngol Rhinol Otol (Stuttg) ; 64(8): 427-9, 1985 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-3862925

RESUMO

Extracanalicular osteomas of the temporal bone represent a rare differential diagnosis of osseous tumours in the ear region in contrast to the common finding of exostoses of the external auditory canal. Basing on a report on a retroauricular osteoma of the squama of the temporal bone treated in the authors' ENT clinic, the morphological and clinical characteristics of this tumour are discussed.


Assuntos
Neoplasias da Orelha/patologia , Osteossarcoma/patologia , Neoplasias Cranianas/patologia , Osso Temporal/patologia , Adulto , Diagnóstico Diferencial , Humanos , Masculino , Osteossarcoma/cirurgia , Neoplasias Cranianas/cirurgia , Osso Temporal/cirurgia , Tomografia Computadorizada por Raios X
19.
Laryngol Rhinol Otol (Stuttg) ; 60(10): 520-4, 1981 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-7345279

RESUMO

The article reports on the use of a new catheter in intraarterial infusion therapy of head and neck tumours. A balloon catheter is inserted into the external carotid artery so that the catheter tip is positioned at the juncture of the artery which provides the blood supply in the tumourous area. Through temporary blockage of the balloon, selective perfusion of the tumour artery with cytostatic drugs is possible. In 10 patients with squamous cell carcinoma of the oral cavity this catheter was used, and the possibilities of this method of selective perfusion explored in contrast to the conventional procedure practised so far.


Assuntos
Antineoplásicos/uso terapêutico , Neoplasias de Cabeça e Pescoço/tratamento farmacológico , Infusões Intra-Arteriais/instrumentação , Angiografia , Carcinoma de Células Escamosas/irrigação sanguínea , Carcinoma de Células Escamosas/tratamento farmacológico , Artéria Carótida Externa , Cateterismo/instrumentação , Neoplasias de Cabeça e Pescoço/irrigação sanguínea , Humanos , Neoplasias Bucais/irrigação sanguínea , Neoplasias Bucais/tratamento farmacológico
20.
Laryngol Rhinol Otol (Stuttg) ; 60(12): 654-7, 1981 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-7345302

RESUMO

Patients with epitympanic cholesteatomas, where the intact canal technique was performed, were observed over 5 resp. 6 years following surgery. While in 27 out of 55 patients a new epitympanic retraction of the tympanic membrane was found, only in 4 cases in these pockets a cholesteatoma developed. This, including the residual cholesteatoma, represents the most important postoperative complication. In tube pressure equalization test we found in 43% of the patients tested an almost normal tube function; in the other patients the tube function is impaired to a varying extent. According to our test results postoperative retraction pockets develop independent of tube function. Even in normal tube function, inserted grommets or perforations of the tympanic membrane - where a sufficient aeration of the middle ear is secured - retraction pockets of varying dimensions may develop. Factors which support the formation of postoperative epitympanic retraction pockets and the part of the tube function are discussed.


Assuntos
Colesteatoma/cirurgia , Membrana Timpânica/patologia , Timpanoplastia/métodos , Testes de Impedância Acústica , Colesteatoma/patologia , Tuba Auditiva/patologia , Humanos , Manometria , Complicações Pós-Operatórias/patologia , Recidiva
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