Detalhe da pesquisa
1.
Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.
Proc Natl Acad Sci U S A
; 115(52): E12265-E12274, 2018 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30541888
2.
Hormonal and spatial control of SUMOylation in the human and mouse adrenal cortex.
FASEB J
; 33(9): 10218-10230, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31208233
3.
EZH2 cooperates with E2F1 to stimulate expression of genes involved in adrenocortical carcinoma aggressiveness.
Br J Cancer
; 121(5): 384-394, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31363169
4.
EZH2 is overexpressed in adrenocortical carcinoma and is associated with disease progression.
Hum Mol Genet
; 25(13): 2789-2800, 2016 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27149985
5.
mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD).
Hum Mol Genet
; 23(20): 5418-28, 2014 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24865460
6.
Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice.
PLoS Genet
; 6(6): e1000980, 2010 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-20548949
7.
Transcriptional control of adrenal steroidogenesis: novel connection between Janus kinase (JAK) 2 protein and protein kinase A (PKA) through stabilization of cAMP response element-binding protein (CREB) transcription factor.
J Biol Chem
; 286(38): 32976-85, 2011 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-21808064
8.
Sexually dimorphic activation of innate antitumor immunity prevents adrenocortical carcinoma development.
Sci Adv
; 8(41): eadd0422, 2022 10 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36240276
9.
Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice.
Nat Commun
; 13(1): 7858, 2022 12 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36543805
10.
Protein kinase A drives paracrine crisis and WNT4-dependent testis tumor in Carney complex.
J Clin Invest
; 131(23)2021 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34850745
11.
PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal.
JCI Insight
; 3(2)2018 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29367455
12.
Adrenocortical development: Lessons from mouse models.
Ann Endocrinol (Paris)
; 79(3): 95-97, 2018 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-29673697
13.
Aldo-Keto Reductases 1B in Adrenal Cortex Physiology.
Front Endocrinol (Lausanne)
; 7: 97, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27499746
14.
PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development.
Nat Commun
; 7: 12751, 2016 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-27624192
15.
Aldose reductases influence prostaglandin F2α levels and adipocyte differentiation in male mouse and human species.
Endocrinology
; 156(5): 1671-84, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25730106
16.
Aldo-Keto Reductases 1B in Endocrinology and Metabolism.
Front Pharmacol
; 3: 148, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22876234
17.
Depressed levels of prostaglandin F2α in mice lacking Akr1b7 increase basal adiposity and predispose to diet-induced obesity.
Diabetes
; 61(11): 2796-806, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22851578
18.
Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7.
J Biochem
; 145(2): 161-8, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-19010934
19.
Aldo keto reductase 1B7 and prostaglandin F2alpha are regulators of adrenal endocrine functions.
PLoS One
; 4(10): e7309, 2009 Oct 07.
Artigo
Inglês
| MEDLINE | ID: mdl-19809495
20.
The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis.
Development
; 134(16): 2947-58, 2007 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-17626060