Detalhe da pesquisa
1.
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.
Nature
; 626(8001): 1073-1083, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38355792
2.
Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.
EMBO J
; 42(17): e111719, 2023 09 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37431963
3.
The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol Cell
; 73(3): 490-504.e6, 2019 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30581145
4.
Tau: a phase in the crowd.
EMBO J
; 41(11): e111425, 2022 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35578810
5.
An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation.
EMBO J
; 41(23): e112338, 2022 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36254605
6.
The seeds of neurodegeneration: prion-like spreading in ALS.
Cell
; 147(3): 498-508, 2011 Oct 28.
Artigo
Inglês
| MEDLINE | ID: mdl-22036560
7.
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Proc Natl Acad Sci U S A
; 119(49): e2123487119, 2022 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36454749
8.
Detection of TDP-43 seeding activity in the olfactory mucosa from patients with frontotemporal dementia.
Alzheimers Dement
; 20(2): 1156-1165, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-37908186
9.
A Gut Feeling about C9ORF72.
Trends Immunol
; 41(9): 755-757, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32800706
10.
FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade.
EMBO Rep
; 22(12): e53877, 2021 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34806807
11.
Structural Transition, Function and Dysfunction of TDP-43 in Neurodegenerative Diseases.
Chimia (Aarau)
; 73(6): 380-390, 2019 May 29.
Artigo
Inglês
| MEDLINE | ID: mdl-31118120
12.
Biology/Disease-Driven Initiative on Protein-Aggregation Diseases of the Human Proteome Project: Goals and Progress to Date.
J Proteome Res
; 17(12): 4072-4084, 2018 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30137990
13.
Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas.
Immunity
; 29(6): 998-1008, 2008 Dec 19.
Artigo
Inglês
| MEDLINE | ID: mdl-19100703
14.
Prion-like propagation as a pathogenic principle in frontotemporal dementia.
J Neurochem
; 138 Suppl 1: 163-83, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27502124
15.
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43.
Proc Natl Acad Sci U S A
; 110(8): E736-45, 2013 Feb 19.
Artigo
Inglês
| MEDLINE | ID: mdl-23382207
16.
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.
Proc Natl Acad Sci U S A
; 110(47): E4530-9, 2013 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-24170860
17.
TDP-43 Proteinopathy Specific Biomarker Development.
Cells
; 12(4)2023 02 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36831264
18.
Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversion.
J Biol Chem
; 286(14): 12149-56, 2011 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-21324909
19.
Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1.
Acta Crystallogr D Biol Crystallogr
; 68(Pt 11): 1501-12, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23090399
20.
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration.
Hum Mol Genet
; 19(R1): R46-64, 2010 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20400460