Detalhe da pesquisa
1.
Intrinsic Fluorescence of the Active and the Inactive Functional Forms of Human Thymidylate Synthase.
Chembiochem
; 22(10): 1800-1810, 2021 05 14.
Artigo
Inglês
| MEDLINE | ID: mdl-33554411
2.
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells.
Int J Mol Sci
; 21(12)2020 Jun 23.
Artigo
Inglês
| MEDLINE | ID: mdl-32585842
3.
Excited-state intramolecular proton transfer in a bioactive flavonoid provides fluorescence observables for recognizing its engagement with target proteins.
Photochem Photobiol Sci
; 18(9): 2270-2280, 2019 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30900698
4.
The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human Ovarian Cancer Cell Lines.
Int J Mol Sci
; 20(24)2019 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31817267
5.
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth.
Molecules
; 24(19)2019 Sep 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31561530
6.
pH-Promoted Release of a Novel Anti-Tumour Peptide by "Stealth" Liposomes: Effect of Nanocarriers on the Drug Activity in Cis-Platinum Resistant Cancer Cells.
Pharm Res
; 35(11): 206, 2018 Sep 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30209680
7.
Optical and photophysical properties of anisole- and cyanobenzene-substituted perylene diimides.
Phys Chem Chem Phys
; 18(6): 4924-41, 2016 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26808207
8.
Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance.
Drug Resist Updat
; 23: 20-54, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26690339
9.
Translational repression of thymidylate synthase by targeting its mRNA.
Nucleic Acids Res
; 41(7): 4159-70, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23423353
10.
Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides.
J Proteome Res
; 13(11): 5250-61, 2014 Nov 07.
Artigo
Inglês
| MEDLINE | ID: mdl-25196676
11.
Linear and nonlinear optical properties of V-shaped D-π-A-π-D chromophores: effects of the incorporation of aromatic rings in the polyenic π-bridges of open-chain ketocyanines.
Phys Chem Chem Phys
; 16(29): 15576-89, 2014 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-24953824
12.
A 5-(difluorenyl)-1,10-phenanthroline-based Ru(II) complex as a coating agent for potential multifunctional gold nanoparticles.
Phys Chem Chem Phys
; 16(28): 14826-33, 2014 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-24921680
13.
Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
Proc Natl Acad Sci U S A
; 108(34): E542-9, 2011 Aug 23.
Artigo
Inglês
| MEDLINE | ID: mdl-21795601
14.
Chemical asymmetry and α and ß polarizabilities of D-A-D' chromophores: a three-state-model and TDDFT-SOS analysis of a penta-heptamethine ketocyanine.
Phys Chem Chem Phys
; 14(12): 4171-80, 2012 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-22354264
15.
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Elife
; 112022 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36475542
16.
Correction to "Mass Spectrometric/Bioinformatic Identification of a Protein Subset That Characterizes the Cellular Activity of Anticancer Peptides".
J Proteome Res
; 15(10): 3944, 2016 10 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27662068
17.
Electronic spectra and (hyper)polarizabilities of non-centrosymmetric D-A-D chromophores. An experimentally based three-state model and a theoretical TDDFT study of ketocyanines.
Phys Chem Chem Phys
; 13(20): 9507-17, 2011 May 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21487586
18.
Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations.
Cancers (Basel)
; 13(9)2021 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33923290
19.
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting.
J Med Chem
; 64(6): 3204-3221, 2021 03 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33710891
20.
SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti-Trypanosoma brucei Agent.
ACS Med Chem Lett
; 10(4): 528-533, 2019 Apr 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30996791