Detalhe da pesquisa
1.
Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer.
Cancer Cell Int
; 24(1): 56, 2024 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38317193
2.
Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.
Mol Cell
; 61(3): 449-460, 2016 Feb 04.
Artigo
Inglês
| MEDLINE | ID: mdl-26748828
3.
Hybrid Self-Assembling Nanoparticles Encapsulating Zoledronic Acid: A Strategy for Fostering Their Clinical Use.
Int J Mol Sci
; 23(9)2022 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35563529
4.
FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma.
J Hepatol
; 75(2): 351-362, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33741397
5.
TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment.
Nucleic Acids Res
; 47(7): 3365-3382, 2019 04 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30698737
6.
HSP90 Inhibition Drives Degradation of FGFR2 Fusion Proteins: Implications for Treatment of Cholangiocarcinoma.
Hepatology
; 69(1): 131-142, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30067876
7.
Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance.
Nucleic Acids Res
; 44(4): 1579-90, 2016 Feb 29.
Artigo
Inglês
| MEDLINE | ID: mdl-26511095
8.
EMICORON: A multi-targeting G4 ligand with a promising preclinical profile.
Biochim Biophys Acta Gen Subj
; 1861(5 Pt B): 1362-1370, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-27838395
9.
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
Nucleic Acids Res
; 43(3): 1759-69, 2015 Feb 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25618850
10.
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
Nucleic Acids Res
; 42(5): 2945-57, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24335081
11.
TRF2 as novel marker of tumor response to taxane-based therapy: from mechanistic insight to clinical implication.
J Exp Clin Cancer Res
; 43(1): 75, 2024 Mar 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38459559
12.
Drug repositioning strategy for the identification of novel telomere-damaging agents: A role for NAMPT inhibitors.
Aging Cell
; 22(11): e13944, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37858982
13.
MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer.
EMBO Mol Med
; 15(1): e16033, 2023 01 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36426578
14.
DARPP-32 and t-DARPP in the development of resistance to anti-HER2 agents. Pre-clinical evidence from the STEP study.
Neoplasia
; 45: 100937, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37769528
15.
Fluorescent nanodiamonds as innovative delivery systems for MiR-34a replacement in breast cancer.
Mol Ther Nucleic Acids
; 33: 127-141, 2023 Sep 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37449042
16.
Anti-tumoural activity of the G-quadruplex ligand pyridostatin against BRCA1/2-deficient tumours.
EMBO Mol Med
; 14(3): e14501, 2022 03 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35107878
17.
TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer.
Cancer Lett
; 533: 215607, 2022 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35240232
18.
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.
Nucleic Acids Res
; 37(16): 5353-64, 2009 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19596811
19.
Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects.
J Exp Clin Cancer Res
; 40(1): 364, 2021 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34784956
20.
Harnessing Omics Approaches on Advanced Preclinical Models to Discovery Novel Therapeutic Targets for the Treatment of Metastatic Colorectal Cancer.
Cancers (Basel)
; 12(7)2020 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32650388