Detalhe da pesquisa
1.
A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXR.
Nucleic Acids Res
; 52(4): 1661-1676, 2024 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38084912
2.
Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein.
Proc Natl Acad Sci U S A
; 120(10): e2217804120, 2023 03 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36848571
3.
Regulation of Nuclear Receptors PXR and CAR by Small Molecules and Signal Crosstalk: Roles in Drug Metabolism and Beyond.
Drug Metab Dispos
; 51(2): 228-236, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36116789
4.
Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR.
Nat Commun
; 15(1): 4054, 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38744881
5.
Ligand flexibility and binding pocket malleability cooperate to allow selective PXR activation by analogs of a promiscuous nuclear receptor ligand.
Structure
; 31(12): 1545-1555.e9, 2023 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37729916
6.
Bacteriological Assessment of the Indoor Air of Different Hospitals of Kathmandu District.
Int J Microbiol
; 2019: 5320807, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31089326