Detalhe da pesquisa
1.
Effects of rolapitant administered orally on the pharmacokinetics of dextromethorphan (CYP2D6), tolbutamide (CYP2C9), omeprazole (CYP2C19), efavirenz (CYP2B6), and repaglinide (CYP2C8) in healthy subjects.
Support Care Cancer
; 27(3): 819-827, 2019 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-30084103
2.
Rolapitant improves quality of life of patients receiving highly or moderately emetogenic chemotherapy.
Support Care Cancer
; 25(1): 85-92, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27557833
3.
Efficacy of the neurokinin-1 receptor antagonist rolapitant in preventing nausea and vomiting in patients receiving carboplatin-based chemotherapy.
Cancer
; 122(15): 2418-25, 2016 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27176138
4.
Pharmacokinetics, Safety, and Tolerability of Rolapitant Administered Intravenously Following Single Ascending and Multiple Ascending Doses in Healthy Subjects.
Clin Pharmacol Drug Dev
; 8(2): 160-171, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29905976
5.
An Open-Label, Randomized, Pivotal Bioequivalence Study of Oral Rolapitant.
Clin Pharmacol Drug Dev
; 8(2): 152-159, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30624856
6.
Compatibility and Stability of VARUBI (Rolapitant) Injectable Emulsion Admixed with Intravenous Palonosetron Hydrochloride Injection and Dexamethasone Sodium Phosphate Injection.
Int J Pharm Compd
; 22(1): 76-85, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29385388
7.
Compatibility and Stability of VARUBI (Rolapitant) Injectable Emulsion Admixed with Intravenous Granisetron Hydrochloride.
Int J Pharm Compd
; 22(1): 86-94, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29385389
8.
Rolapitant for the prevention of nausea in patients receiving highly or moderately emetogenic chemotherapy.
Cancer Med
; 7(7): 2943-2950, 2018 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-29790666
9.
Effects of Rolapitant Administered Intravenously on the Pharmacokinetics of a Modified Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan) in Healthy Subjects.
J Clin Pharmacol
; 58(8): 1074-1083, 2018 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-29693712
10.
Efficacy and safety of rolapitant for prevention of chemotherapy-induced nausea and vomiting over multiple cycles of moderately or highly emetogenic chemotherapy.
Eur J Cancer
; 57: 23-30, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26851398