Detalhe da pesquisa
1.
Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins.
Immunity
; 54(4): 781-796.e4, 2021 04 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33675683
2.
JFH1-based Core-NS2 genotype variants of HCV with genetic stability in vivo and in vitro: Important tools in evaluation of virus neutralization.
Hepatology
; 2024 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38652584
3.
Identification of novel neutralizing determinants for protection against HCV.
Hepatology
; 77(3): 982-996, 2023 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36056620
4.
Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice.
Gut
; 72(3): 560-572, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35918103
5.
In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus.
PLoS Pathog
; 17(7): e1009720, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34280245
6.
Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice.
J Hepatol
; 76(5): 1051-1061, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34990750
7.
Hypervariable region 1 and N-linked glycans of hepatitis C regulate virion neutralization by modulating envelope conformations.
Proc Natl Acad Sci U S A
; 116(20): 10039-10047, 2019 05 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31040211
8.
Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design.
PLoS Pathog
; 15(5): e1007772, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31100098
9.
Hepatitis C Virus Escape Studies of Human Antibody AR3A Reveal a High Barrier to Resistance and Novel Insights on Viral Antibody Evasion Mechanisms.
J Virol
; 93(4)2019 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30487284
10.
Hepatitis C Virus-Escape Studies for Human Monoclonal Antibody AR4A Reveal Isolate-Specific Resistance and a High Barrier to Resistance.
J Infect Dis
; 219(1): 68-79, 2019 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30102355
11.
Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry.
J Virol
; 92(10)2018 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29491159
12.
Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A.
PLoS Pathog
; 13(2): e1006214, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28231271
13.
Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity.
Hepatology
; 64(6): 1881-1892, 2016 12.
Artigo
Inglês
| MEDLINE | ID: mdl-27351277
14.
HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice.
Gut
; 65(12): 1988-1997, 2016 12.
Artigo
Inglês
| MEDLINE | ID: mdl-26589670
15.
Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant.
J Virol
; 89(15): 7758-75, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25995244
16.
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus.
J Virol
; 88(3): 1725-39, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24257605
17.
Breadth of neutralization and synergy of clinically relevant human monoclonal antibodies against HCV genotypes 1a, 1b, 2a, 2b, 2c, and 3a.
Hepatology
; 60(5): 1551-62, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25043937
18.
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus.
Proc Natl Acad Sci U S A
; 109(16): 6205-10, 2012 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22492964
19.
Cooperativity in virus neutralization by human monoclonal antibodies to two adjacent regions located at the amino terminus of hepatitis C virus E2 glycoprotein.
J Virol
; 87(1): 37-51, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23097455
20.
Analysis of functional differences between hepatitis C virus NS5A of genotypes 1-7 in infectious cell culture systems.
PLoS Pathog
; 8(5): e1002696, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22654662