Detalhe da pesquisa
1.
Codon optimality is a major determinant of mRNA stability.
Cell
; 160(6): 1111-24, 2015 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-25768907
2.
Systemic mRNA Therapy for the Treatment of Fabry Disease: Preclinical Studies in Wild-Type Mice, Fabry Mouse Model, and Wild-Type Non-human Primates.
Am J Hum Genet
; 104(4): 625-637, 2019 04 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30879639
3.
mRNA structure regulates protein expression through changes in functional half-life.
Proc Natl Acad Sci U S A
; 116(48): 24075-24083, 2019 11 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31712433
4.
Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4-/- mouse model of PFIC3.
J Hepatol
; 74(6): 1416-1428, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33340584
5.
Oligonucleotide Sequence Mapping of Large Therapeutic mRNAs via Parallel Ribonuclease Digestions and LC-MS/MS.
Anal Chem
; 91(13): 8500-8506, 2019 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31129964
6.
High density lipoprotein promotes nascent apolipoprotein A-V secretion from mRNA transfected cells.
Biochem Biophys Res Commun
; 512(2): 387-391, 2019 04 30.
Artigo
Inglês
| MEDLINE | ID: mdl-30902391
7.
N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density.
Nucleic Acids Res
; 45(10): 6023-6036, 2017 Jun 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28334758
8.
TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites.
RNA
; 16(11): 2239-51, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-20855539
9.
Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine.
Front Immunol
; 12: 772864, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34956199
10.
A multiclade env-gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques.
Nat Med
; 27(12): 2234-2245, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34887575
11.
mRNA therapy restores euglycemia and prevents liver tumors in murine model of glycogen storage disease.
Nat Commun
; 12(1): 3090, 2021 05 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34035281
12.
Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia.
Cell Rep
; 21(12): 3548-3558, 2017 Dec 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29262333
13.
Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia.
Cell Rep
; 24(9): 2520, 2018 Aug 28.
Artigo
Inglês
| MEDLINE | ID: mdl-30157442
14.
Distinct and overlapping functions of MRP1/2 and RBP16 in mitochondrial RNA metabolism.
Mol Cell Biol
; 29(19): 5214-25, 2009 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-19620277
15.
A type III protein arginine methyltransferase from the protozoan parasite Trypanosoma brucei.
J Biol Chem
; 284(17): 11590-600, 2009 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-19254949
16.
Nuclear Exclusion of the HIV-1 host defense factor APOBEC3G requires a novel cytoplasmic retention signal and is not dependent on RNA binding.
J Biol Chem
; 283(12): 7320-7, 2008 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-18165230
17.
TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages.
J Biol Chem
; 283(34): 23016-25, 2008 Aug 22.
Artigo
Inglês
| MEDLINE | ID: mdl-18583347