Machine learning predicts upper secondary education dropout as early as the end of primary school.

Education plays a pivotal role in alleviating poverty, driving economic growth, and empowering individuals, thereby significantly influencing societal and personal development. However, the persistent issue of school dropout poses a significant challenge, with its effects extending beyond the individual. While previous research has employed machine learning for dropout classification, these studies often suffer from a short-term focus, relying on data collected only a few years into the study period. This study expanded the modeling horizon by utilizing a 13-year longitudinal dataset, encompassing data from kindergarten to Grade 9. Our methodology incorporated a comprehensive range of parameters, including students' academic and cognitive skills, motivation, behavior, well-being, and officially recorded dropout data. The machine learning models developed in this study demonstrated notable classification ability, achieving a mean area under the curve (AUC) of 0.61 with data up to Grade 6 and an improved AUC of 0.65 with data up to Grade 9. Further data collection and independent correlational and causal analyses are crucial. In future iterations, such models may have the potential to proactively support educators' processes and existing protocols for identifying at-risk students, thereby potentially aiding in the reinvention of student retention and success strategies and ultimately contributing to improved educational outcomes.

Improved accuracy in colorectal cancer tissue decomposition through refinement of established deep learning solutions.

Hematoxylin and eosin-stained biopsy slides are regularly available for colorectal cancer patients. These slides are often not used to define objective biomarkers for patient stratification and treatment selection. Standard biomarkers often pertain to costly and slow genetic tests. However, recent work has shown that relevant biomarkers can be extracted from these images using convolutional neural networks (CNNs). The CNN-based biomarkers predicted colorectal cancer patient outcomes comparably to gold standards. Extracting CNN-biomarkers is fast, automatic, and of minimal cost. CNN-based biomarkers rely on the ability of CNNs to recognize distinct tissue types from microscope whole slide images. The quality of these biomarkers (coined 'Deep Stroma') depends on the accuracy of CNNs in decomposing all relevant tissue classes. Improving tissue decomposition accuracy is essential for improving the prognostic potential of CNN-biomarkers. In this study, we implemented a novel training strategy to refine an established CNN model, which then surpassed all previous solutions . We obtained a 95.6% average accuracy in the external test set and 99.5% in the internal test set. Our approach reduced errors in biomarker-relevant classes, such as Lymphocytes, and was the first to include interpretability methods. These methods were used to better apprehend our model's limitations and capabilities.

DeepFake knee osteoarthritis X-rays from generative adversarial neural networks deceive medical experts and offer augmentation potential to automatic classification.

Recent developments in deep learning have impacted medical science. However, new privacy issues and regulatory frameworks have hindered medical data sharing and collection. Deep learning is a very data-intensive process for which such regulatory limitations limit the potential for new breakthroughs and collaborations. However, generating medically accurate synthetic data can alleviate privacy issues and potentially augment deep learning pipelines. This study presents generative adversarial neural networks capable of generating realistic images of knee joint X-rays with varying osteoarthritis severity. We offer 320,000 synthetic (DeepFake) X-ray images from training with 5,556 real images. We validated our models regarding medical accuracy with 15 medical experts and for augmentation effects with an osteoarthritis severity classification task. We devised a survey of 30 real and 30 DeepFake images for medical experts. The result showed that on average, more DeepFakes were mistaken for real than the reverse. The result signified sufficient DeepFake realism for deceiving the medical experts. Finally, our DeepFakes improved classification accuracy in an osteoarthritis severity classification task with scarce real data and transfer learning. In addition, in the same classification task, we replaced all real training data with DeepFakes and suffered only a [Formula: see text] loss from baseline accuracy in classifying real osteoarthritis X-rays.