Detalhe da pesquisa
1.
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity.
Cell
; 180(1): 188-204.e22, 2020 01 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31883794
2.
Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114.
J Biol Chem
; 299(7): 104912, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37307916
3.
Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1.
Brain
; 146(10): 4217-4232, 2023 10 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37143315
4.
Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites.
Int J Mol Sci
; 24(18)2023 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37761979
5.
Combinatorial model of amyloid ß and tau reveals synergy between amyloid deposits and tangle formation.
Neuropathol Appl Neurobiol
; 48(2): e12779, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34825397
6.
Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice.
Acta Neuropathol
; 143(6): 663-685, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35488930
7.
TREM2 risk variants are associated with atypical Alzheimer's disease.
Acta Neuropathol
; 144(6): 1085-1102, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36112222
8.
Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
EMBO Rep
; 21(3): e48530, 2020 03 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32003148
9.
Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples.
Acta Neuropathol
; 138(4): 613-630, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31350575
10.
High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia.
Acta Neuropathol
; 132(3): 361-75, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27393312
11.
Nuclear translocation uncovers the amyloid peptide Aß42 as a regulator of gene transcription.
J Biol Chem
; 289(29): 20182-91, 2014 Jul 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24878959
12.
Lymphocytes modulate innate immune responses and neuronal damage in experimental meningitis.
Infect Immun
; 83(1): 259-67, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25348636
13.
Hyperacetylation mimetics within the tau filament core inhibits prion-like propagation of misfolded tau.
bioRxiv
; 2024 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38659970
14.
Targeted brain-specific tauopathy compromises peripheral skeletal muscle integrity and function.
Aging Brain
; 5: 100110, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38419621
15.
Disease and brain region specific immune response profiles in neurodegenerative diseases with pure and mixed protein pathologies.
Acta Neuropathol Commun
; 12(1): 54, 2024 Apr 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38581050
16.
Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity.
bioRxiv
; 2024 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38712030
17.
Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations.
bioRxiv
; 2024 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38659743
18.
Luminescent conjugated oligothiophenes for sensitive fluorescent assignment of protein inclusion bodies.
Chembiochem
; 14(5): 607-16, 2013 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23450708
19.
Impairment of immunoproteasome function by ß5i/LMP7 subunit deficiency results in severe enterovirus myocarditis.
PLoS Pathog
; 7(9): e1002233, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21909276
20.
Microglia actions in Alzheimer's disease.
Acta Neuropathol
; 126(4): 461-77, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24224195