Detalhe da pesquisa
1.
The Isoleucine at Position 118 in Transmembrane 2 Is Responsible for the Selectivity of Xamoterol, Nebivolol, and ICI89406 for the Human ß1-Adrenoceptor.
Mol Pharmacol
; 103(2): 89-99, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36351797
2.
Salmeterol's extreme ß2 selectivity is due to residues in both extracellular loops and transmembrane domains.
Mol Pharmacol
; 87(1): 103-20, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25324048
3.
Identification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human ß1-adrenoceptor.
Mol Pharmacol
; 85(5): 811-29, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24608857
4.
The signaling and selectivity of α-adrenoceptor agonists for the human α2A, α2B and α2C-adrenoceptors and comparison with human α1 and ß-adrenoceptors.
Pharmacol Res Perspect
; 10(5): e01003, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36101495
5.
The affinity and selectivity of α-adrenoceptor antagonists, antidepressants and antipsychotics for the human α2A, α2B, and α2C-adrenoceptors and comparison with human α1 and ß-adrenoceptors.
Pharmacol Res Perspect
; 10(2): e00936, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35224877
6.
The selectivity of α-adrenoceptor agonists for the human α1A, α1B, and α1D-adrenoceptors.
Pharmacol Res Perspect
; 9(4): e00799, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34355529
7.
The affinity and selectivity of α-adrenoceptor antagonists, antidepressants, and antipsychotics for the human α1A, α1B, and α1D-adrenoceptors.
Pharmacol Res Perspect
; 8(4): e00602, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32608144
8.
Role of key transmembrane residues in agonist and antagonist actions at the two conformations of the human beta1-adrenoceptor.
Mol Pharmacol
; 74(5): 1246-60, 2008 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-18687809
9.
Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human ß1-adrenoceptor.
PLoS One
; 8(11): e77582, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24250787
10.
The pharmacological effects of the thermostabilising (m23) mutations and intra and extracellular (ß36) deletions essential for crystallisation of the turkey ß-adrenoceptor.
Naunyn Schmiedebergs Arch Pharmacol
; 384(1): 71-91, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-21547538