Detalhe da pesquisa
1.
DNA mismatches reveal conformational penalties in protein-DNA recognition.
Nature
; 587(7833): 291-296, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33087930
2.
UV irradiation remodels the specificity landscape of transcription factors.
Proc Natl Acad Sci U S A
; 120(11): e2217422120, 2023 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36888663
3.
Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors.
Nature
; 558(7711): E5, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29849140
4.
IL6Myc mouse is an immunocompetent model for the development of aggressive multiple myeloma.
Haematologica
; 108(12): 3372-3383, 2023 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37439384
5.
Metabolic gatekeeper function of B-lymphoid transcription factors.
Nature
; 542(7642): 479-483, 2017 02 23.
Artigo
Inglês
| MEDLINE | ID: mdl-28192788
6.
Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression.
Genome Res
; 29(11): 1753-1765, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31519741
7.
Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes.
Nucleic Acids Res
; 48(9): 5037-5053, 2020 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32315032
8.
Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia.
Proc Natl Acad Sci U S A
; 116(8): 3052-3061, 2019 02 19.
Artigo
Inglês
| MEDLINE | ID: mdl-30733284
9.
SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site.
Genome Res
; 28(1): 111-121, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29196557
10.
Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.
Blood
; 129(22): 3000-3008, 2017 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28424165
11.
JUNB is a key transcriptional modulator of macrophage activation.
J Immunol
; 194(1): 177-86, 2015 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25472994
12.
Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops.
J Biol Chem
; 290(32): 19756-69, 2015 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26088140
13.
A naturally occurring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms.
Proc Natl Acad Sci U S A
; 110(44): 17826-31, 2013 Oct 29.
Artigo
Inglês
| MEDLINE | ID: mdl-24127590
14.
Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.
Am J Physiol Endocrinol Metab
; 308(2): E144-58, 2015 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25406264
15.
Glucocorticoids and Cancer.
Adv Exp Med Biol
; 872: 315-33, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26216001
16.
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles.
Nat Chem Biol
; 8(5): 471-6, 2012 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22466421
17.
PI3Kδ inhibition potentiates glucocorticoids in B-lymphoblastic leukemia by decreasing receptor phosphorylation and enhancing gene regulation.
bioRxiv
; 2023 Aug 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36798391
18.
PI3Kδ Inhibition Potentiates Glucocorticoids in B-lymphoblastic Leukemia by Decreasing Receptor Phosphorylation and Enhancing Gene Regulation.
Cancers (Basel)
; 16(1)2023 Dec 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38201570
19.
Transcriptional coactivation by EHMT2 restricts glucocorticoid-induced insulin resistance in a study with male mice.
Nat Commun
; 14(1): 3143, 2023 05 30.
Artigo
Inglês
| MEDLINE | ID: mdl-37253782
20.
De novo distillation of thermodynamic affinity from deep learning regulatory sequence models of in vivo protein-DNA binding.
bioRxiv
; 2023 May 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37214836