Detalhe da pesquisa
1.
Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity.
PLoS Pathog
; 14(8): e1007261, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30118512
2.
The Essential Role of Cholesterol Metabolism in the Intracellular Survival of Mycobacterium leprae Is Not Coupled to Central Carbon Metabolism and Energy Production.
J Bacteriol
; 197(23): 3698-707, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26391209
3.
Inhibition of the first step in synthesis of the mycobacterial cell wall core, catalyzed by the GlcNAc-1-phosphate transferase WecA, by the novel caprazamycin derivative CPZEN-45.
J Biol Chem
; 288(42): 30309-30319, 2013 Oct 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23986448
4.
SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis.
Eur J Med Chem
; 249: 115125, 2023 Mar 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36682292
5.
Mycobacterial MenG: Partial Purification, Characterization, and Inhibition.
ACS Infect Dis
; 8(12): 2430-2440, 2022 12 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36417754
6.
Synthetic Sansanmycin Analogues as Potent Mycobacterium tuberculosis Translocase I Inhibitors.
J Med Chem
; 64(23): 17326-17345, 2021 12 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34845906
7.
Characterization of MenA (isoprenyl diphosphate:1,4-dihydroxy-2-naphthoate isoprenyltransferase) from Mycobacterium tuberculosis.
PLoS One
; 14(4): e0214958, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30978223
8.
Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis.
Nat Commun
; 8: 14414, 2017 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28248311
9.
Multitarget drug discovery for tuberculosis and other infectious diseases.
J Med Chem
; 57(7): 3126-39, 2014 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24568559
10.
Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies.
J Med Chem
; 54(13): 4721-34, 2011 Jul 14.
Artigo
Inglês
| MEDLINE | ID: mdl-21561155
11.
The transcription factor Spn1 regulates gene expression via a highly conserved novel structural motif.
J Mol Biol
; 404(1): 1-15, 2010 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-20875428