Detalhe da pesquisa
1.
Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma.
J Biol Chem
; 299(12): 105418, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37923138
2.
Targeting BRD/BET proteins inhibits adaptive kinome upregulation and enhances the effects of BRAF/MEK inhibitors in melanoma.
Br J Cancer
; 122(6): 789-800, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31932756
3.
Murine Cytomegalovirus Infection of Melanoma Lesions Delays Tumor Growth by Recruiting and Repolarizing Monocytic Phagocytes in the Tumor.
J Virol
; 93(20)2019 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31375579
4.
SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death.
Mol Cancer Res
; 22(2): 209-220, 2024 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37847239
5.
Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP signaling in dormant disseminated uveal melanoma.
bioRxiv
; 2024 Mar 08.
Artigo
Inglês
| MEDLINE | ID: mdl-38496663
6.
Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress.
Sci Signal
; 17(840): eadn8376, 2024 Jun 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38861613
7.
Gene signature reveals decreased SOX10-dependent transcripts in malignant cells from immune checkpoint inhibitor-resistant cutaneous melanomas.
iScience
; 26(9): 107472, 2023 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37636077
8.
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth.
Cancers (Basel)
; 15(13)2023 Jun 30.
Artigo
Inglês
| MEDLINE | ID: mdl-37444561
9.
A Genome-Wide Screen Identifies PDPK1 as a Target to Enhance the Efficacy of MEK1/2 Inhibitors in NRAS Mutant Melanoma.
Cancer Res
; 82(14): 2625-2639, 2022 07 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35657206
10.
Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma.
Mol Cancer Res
; 20(8): 1260-1271, 2022 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35426938
11.
The AMP-dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma.
Pigment Cell Melanoma Res
; 35(1): 78-87, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34347929
12.
Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma.
Oncogene
; 41(8): 1129-1139, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35046531
13.
Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma.
Nat Commun
; 13(1): 1381, 2022 03 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35296667
14.
Roles of the BAP1 Tumor Suppressor in Cell Metabolism.
Cancer Res
; 81(11): 2807-2814, 2021 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33446574
15.
SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects.
Cell Rep
; 37(10): 110085, 2021 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34879275
16.
BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors.
Oncogene
; 40(3): 618-632, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33208912
17.
Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma.
Mol Cancer Ther
; 19(8): 1719-1726, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32430489
18.
Targeting PHGDH Upregulation Reduces Glutathione Levels and Resensitizes Resistant NRAS-Mutant Melanoma to MAPK Kinase Inhibition.
J Invest Dermatol
; 140(11): 2242-2252.e7, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32389536
19.
Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis.
Cancer Discov
; 10(2): 254-269, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31796433
20.
FOXD3 Regulates VISTA Expression in Melanoma.
Cell Rep
; 30(2): 510-524.e6, 2020 01 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31940493