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1.
Vet Parasitol ; 38(1): 75-9, 1991 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-1827221

RESUMO

The efficacy of levamisole pour-on against Dictyocaulus viviparus was compared to that of subcutaneous levamisole injection. Eighteen calves were raised individually and artifically infected with D. viviparus larvae. Faecal samples were collected 27 and 28 days later and larvae per gram (l.p.g.) determined. The animals were then divided into three comparable groups. Group 1 animals remained untreated as controls. Group 2 animals received levamisole 10% w/v subcutaneous injection at a dose of 5 mg kg-1 and Group 3 received levamisole pour-on 20% w/v at a rate of 10 mg kg-1 applied transdermally. Results of l.p.g. measurements from faecal samples taken 7 and 8 days post-treatment indicated a dramatic reduction in the worm burden of animals in both treatment groups. Necropsies at 14 days post-treatment revealed few adult worms in these groups, indicating a 99 and 98% kill rate for pouron and subcutaneous injection, respectively.


Assuntos
Doenças dos Bovinos/tratamento farmacológico , Infecções por Dictyocaulus/tratamento farmacológico , Levamisol/uso terapêutico , Administração Tópica , Animais , Bovinos , Injeções Subcutâneas/veterinária , Levamisol/administração & dosagem
2.
Vet Rec ; 129(9): 189-92, 1991 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-1957469

RESUMO

The strategic use of anthelmintics in the control of infections of Haemonchus contortus in ewes and lambs, was investigated in a series of paddock trials. The levels of infection and clinical signs associated with the presence of either benzimidazole-resistant or benzimidazole-susceptible strains of H contortus in lambs were controlled by regular drenching with levamisole or mebendazole, respectively, or by the strategic use of closantel in combination with mebendazole. In the latter case, control was achieved by dosing either the ewes in the early part of the grazing season, or the lambs from June onwards. It was concluded that worm control strategies based on closantel could provide effective control of both benzimidazole-susceptible and benzimidazole-resistant strains of H contortus on farms in the United Kingdom.


Assuntos
Anti-Helmínticos/uso terapêutico , Hemoncose/veterinária , Doenças dos Ovinos/prevenção & controle , Animais , Anti-Helmínticos/administração & dosagem , Quimioterapia Combinada , Fezes/parasitologia , Feminino , Hemoncose/prevenção & controle , Levamisol/administração & dosagem , Levamisol/uso terapêutico , Mebendazol/administração & dosagem , Mebendazol/uso terapêutico , Contagem de Ovos de Parasitas/veterinária , Chuva , Salicilanilidas/administração & dosagem , Salicilanilidas/uso terapêutico , Ovinos , Temperatura , Reino Unido , Aumento de Peso
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