Detalhe da pesquisa
1.
What causes hidradenitis suppurativa ?-15 years after.
Exp Dermatol
; 29(12): 1154-1170, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33058306
2.
Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor.
J Med Chem
; 67(6): 5093-5108, 2024 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38476002
3.
IL-26 Potentiates Type 2 Skin Inflammation in the Presence of IL-1ß.
J Invest Dermatol
; 2024 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38237730
4.
LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trial.
Clin Transl Sci
; 17(2): e13724, 2024 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38407540
5.
A virus-like particle-based anti-nerve growth factor vaccine reduces inflammatory hyperalgesia: potential long-term therapy for chronic pain.
J Immunol
; 186(3): 1769-80, 2011 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21191068
6.
Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase.
J Med Chem
; 66(23): 16410-16425, 2023 12 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38015154
7.
Adriforant is a functional antagonist of histamine receptor 4 and attenuates itch and skin inflammation in mice.
Eur J Pharmacol
; 945: 175533, 2023 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36690055
8.
Disease Association of AntiâCarboxyethyl Lysine Autoantibodies in Hidradenitis Suppurativa.
J Invest Dermatol
; 143(2): 273-283.e12, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36116506
9.
Drug discovery strategies for novel leukotriene A4 hydrolase inhibitors.
Expert Opin Drug Discov
; 16(12): 1483-1495, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34191664
10.
Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase.
J Med Chem
; 64(4): 1889-1903, 2021 02 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33592148
11.
Lipidomics Profiling of Hidradenitis Suppurativa Skin Lesions Reveals Lipoxygenase Pathway Dysregulation and Accumulation of Proinflammatory Leukotriene B4.
J Invest Dermatol
; 140(12): 2421-2432.e10, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32387270
12.
Transport of Streptococcus pneumoniae capsular polysaccharide in MHC Class II tubules.
PLoS Pathog
; 3(3): e32, 2007 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-17367207
13.
Comment on "An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness".
Sci Transl Med
; 11(497)2019 06 19.
Artigo
Inglês
| MEDLINE | ID: mdl-31217337
14.
A novel strategy for the discovery of MHC class II-restricted tumor antigens: identification of a melanotransferrin helper T-cell epitope.
Cancer Res
; 65(21): 10068-78, 2005 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-16267033
15.
Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.
Sci Rep
; 7(1): 13591, 2017 10 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29051536
16.
Vaccines against non-communicable diseases.
Curr Opin Immunol
; 22(3): 391-6, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20338740
17.
IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium.
PLoS One
; 5(11): e13804, 2010 Nov 23.
Artigo
Inglês
| MEDLINE | ID: mdl-21124903
18.
Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis.
Eur J Immunol
; 36(11): 2857-67, 2006 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-17048275
19.
Neutralization of IL-17 by active vaccination inhibits IL-23-dependent autoimmune myocarditis.
Eur J Immunol
; 36(11): 2849-56, 2006 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-17039570
20.
Melanoma cell necrosis facilitates transfer of specific sets of antigens onto MHC class II molecules of dendritic cells.
Eur J Immunol
; 35(10): 2826-39, 2005 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16163671