Detalhe da pesquisa
1.
Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues.
Mol Cell
; 64(5): 982-992, 2016 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27889451
2.
Genetic determinants of gut microbiota composition and bile acid profiles in mice.
PLoS Genet
; 15(8): e1008073, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31465442
3.
Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion.
J Biol Chem
; 293(16): 5860-5877, 2018 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29496998
4.
The Transcription Factor Nfatc2 Regulates ß-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.
PLoS Genet
; 12(12): e1006466, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-27935966
5.
Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion.
J Biol Chem
; 289(36): 25276-86, 2014 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25002582
6.
Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets.
PLoS Genet
; 8(12): e1003107, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-23236292
7.
Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.
Nat Genet
; 38(6): 688-93, 2006 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-16682971
8.
A potent α/ß-peptide analogue of GLP-1 with prolonged action in vivo.
J Am Chem Soc
; 136(37): 12848-51, 2014 Sep 17.
Artigo
Inglês
| MEDLINE | ID: mdl-25191938
9.
Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.
PLoS Genet
; 7(10): e1002323, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21998599
10.
Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.
Nat Microbiol
; 8(3): 424-440, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36759753
11.
Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis.
J Lipid Res
; 53(8): 1493-501, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22628617
12.
ß Cell-specific deletion of Zfp148 improves nutrient-stimulated ß cell Ca2+ responses.
JCI Insight
; 7(10)2022 05 23.
Artigo
Inglês
| MEDLINE | ID: mdl-35603790
13.
Loss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity.
Am J Physiol Endocrinol Metab
; 301(3): E517-26, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21673305
14.
BTBR Ob/Ob mutant mice model progressive diabetic nephropathy.
J Am Soc Nephrol
; 21(9): 1533-42, 2010 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-20634301
15.
Identification of direct transcriptional targets of NFATC2 that promote ß cell proliferation.
J Clin Invest
; 131(21)2021 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34491912
16.
A large-scale genome-lipid association map guides lipid identification.
Nat Metab
; 2(10): 1149-1162, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32958938
17.
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice.
Mamm Genome
; 20(8): 476-85, 2009 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-19727952
18.
Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function.
Mol Endocrinol
; 22(12): 2716-28, 2008 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-18845673
19.
Gene loci associated with insulin secretion in islets from non-diabetic mice.
J Clin Invest
; 129(10): 4419-4432, 2019 07 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31343992
20.
Genetic Drivers of Pancreatic Islet Function.
Genetics
; 209(1): 335-356, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29567659