Detalhe da pesquisa
1.
Deep learning-enabled natural language processing to identify directional pharmacokinetic drug-drug interactions.
BMC Bioinformatics
; 24(1): 413, 2023 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37914988
2.
Effect of Paroxetine or Quetiapine Combined With Oxycodone vs Oxycodone Alone on Ventilation During Hypercapnia: A Randomized Clinical Trial.
JAMA
; 328(14): 1405-1414, 2022 10 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36219407
3.
Predicting potential adverse events using safety data from marketed drugs.
BMC Bioinformatics
; 21(1): 163, 2020 Apr 29.
Artigo
Inglês
| MEDLINE | ID: mdl-32349656
4.
Aggregation and analysis of indication-symptom relationships for drugs approved in the USA.
Eur J Clin Pharmacol
; 76(9): 1291-1299, 2020 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-32495081
5.
PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development.
PLoS Comput Biol
; 14(12): e1006614, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30532240
6.
Updates on the web-based VIOLIN vaccine database and analysis system.
Nucleic Acids Res
; 42(Database issue): D1124-32, 2014 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24259431
7.
DNAVaxDB: the first web-based DNA vaccine database and its data analysis.
BMC Bioinformatics
; 15 Suppl 4: S2, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-25104313
8.
Algorithmic Identification of Treatment-Emergent Adverse Events From Clinical Notes Using Large Language Models: A Pilot Study in Inflammatory Bowel Disease.
Clin Pharmacol Ther
; 115(6): 1391-1399, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38459719
9.
The expanding universe of NUTM1 fusions in pediatric cancer.
Clin Transl Sci
; 16(8): 1331-1339, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37082775
10.
Rewiring Drug Research and Development through Human Data-Driven Discovery (HD3).
Pharmaceutics
; 15(6)2023 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37376121
11.
Algorithmic identification of treatment-emergent adverse events from clinical notes using large language models: a pilot study in inflammatory bowel disease.
medRxiv
; 2023 Sep 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37732220
12.
Ontology-Based Classification and Analysis of Adverse Events Associated With the Usage of Chloroquine and Hydroxychloroquine.
Front Pharmacol
; 13: 812338, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35401219
13.
Analysis of secondary pharmacology assays received by the US Food and Drug Administration.
J Pharmacol Toxicol Methods
; 117: 107205, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35926773
14.
A network paradigm predicts drug synergistic effects using downstream protein-protein interactions.
CPT Pharmacometrics Syst Pharmacol
; 11(11): 1527-1538, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36204824
15.
New science, drug regulation, and emergent public health issues: The work of FDA's division of applied regulatory science.
Front Med (Lausanne)
; 9: 1109541, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36743666
16.
Aggregation and analysis of secondary pharmacology data from investigational new drug submissions at the US Food and Drug Administration.
J Pharmacol Toxicol Methods
; 111: 107098, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34229067
17.
Target Adverse Event Profiles for Predictive Safety in the Postmarket Setting.
Clin Pharmacol Ther
; 109(5): 1232-1243, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33090463
18.
VaximmutorDB: A Web-Based Vaccine Immune Factor Database and Its Application for Understanding Vaccine-Induced Immune Mechanisms.
Front Immunol
; 12: 639491, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33777032
19.
Effects of sedative psychotropic drugs combined with oxycodone on respiratory depression in the rat.
Clin Transl Sci
; 14(6): 2208-2219, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34080766
20.
Evaluating kratom alkaloids using PHASE.
PLoS One
; 15(3): e0229646, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32126112