Detalhe da pesquisa
1.
Erythromelalgia caused by the missense mutation p.Arg220Pro in an alternatively spliced exon of SCN9A (NaV1.7).
Hum Mol Genet
; 33(2): 103-109, 2024 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37721535
2.
Novel Scorpion Toxin ω-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via CaV3.3 and CaV3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain.
Int J Mol Sci
; 25(9)2024 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38731963
3.
Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox.
J Biol Chem
; 298(8): 102218, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35780839
4.
Changes in Potency and Subtype Selectivity of Bivalent NaV Toxins are Knot-Specific.
Bioconjug Chem
; 34(6): 1072-1083, 2023 06 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37262436
5.
GRIN1 variants associated with neurodevelopmental disorders reveal channel gating pathomechanisms.
Epilepsia
; 64(12): 3377-3388, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37734923
6.
Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3ß4 and α7 nicotinic acetylcholine receptors.
J Biol Chem
; 295(20): 7096-7112, 2020 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32234761
7.
Characterisation of d-Conotoxin TxVIA as a Mammalian T-Type Calcium Channel Modulator.
Mar Drugs
; 18(7)2020 Jun 30.
Artigo
Inglês
| MEDLINE | ID: mdl-32629781
8.
Synthesis, Pharmacological and Structural Characterization of Novel Conopressins from Conus miliaris.
Mar Drugs
; 18(3)2020 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32155768
9.
Synthesis of Pseudellone Analogs and Characterization as Novel T-type Calcium Channel Blockers.
Mar Drugs
; 16(12)2018 Nov 28.
Artigo
Inglês
| MEDLINE | ID: mdl-30487473
10.
Correction: Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3ß4 and α7 nicotinic acetylcholine receptors.
J Biol Chem
; 295(26): 8872, 2020 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32591448
11.
Extracellular surface residues of the α1B-adrenoceptor critical for G protein-coupled receptor function.
Mol Pharmacol
; 87(1): 121-9, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25352041
12.
Conopeptide ρ-TIA defines a new allosteric site on the extracellular surface of the α1B-adrenoceptor.
J Biol Chem
; 288(3): 1814-27, 2013 Jan 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23184947
13.
Structural Conformation and Activity of Spider-Derived Inhibitory Cystine Knot Peptide Pn3a Are Modulated by pH.
ACS Omega
; 8(29): 26276-26286, 2023 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37521635
14.
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.
Nat Commun
; 14(1): 2442, 2023 04 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37117223
15.
Diindolylmethane Derivatives: New Selective Blockers for T-Type Calcium Channels.
Membranes (Basel)
; 12(8)2022 Jul 30.
Artigo
Inglês
| MEDLINE | ID: mdl-36005664
16.
Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation.
Eur J Pharmacol
; 925: 175013, 2022 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35537491
17.
The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E.
Br J Pharmacol
; 179(20): 4878-4896, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35818835
18.
Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain.
PLoS One
; 16(3): e0243645, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33667217
19.
The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation.
Front Pharmacol
; 12: 789570, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-35095499
20.
T-type Calcium Channels in Health and Disease.
Curr Med Chem
; 27(19): 3098-3122, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-30277145