Detalhe da pesquisa
1.
Mitochondrial base editor induces substantial nuclear off-target mutations.
Nature
; 606(7915): 804-811, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35551512
2.
Engineering APOBEC3A deaminase for highly accurate and efficient base editing.
Nat Chem Biol
; 2024 Mar 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38553609
3.
Detect-seq, a chemical labeling and biotin pull-down approach for the unbiased and genome-wide off-target evaluation of programmable cytosine base editors.
Nat Protoc
; 18(7): 2221-2255, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37277562
4.
DddA homolog search and engineering expand sequence compatibility of mitochondrial base editing.
Nat Commun
; 14(1): 874, 2023 02 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36797253
5.
The trans DNA cleavage activity of Cas12a provides no detectable immunity against plasmid or phage.
Front Genome Ed
; 4: 929929, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35958049