'Using Q-methodology to Explore What is Valued from Child Sexual Exploitation Services: The Importance of Safety'.

Child Sexual Exploitation (CSE) is a complex international issue requiring specialist multi-agency support. There is evidence that survivors of CSE are likely to experience mental health difficulties and have long-term psychological needs in response to trauma. However evidence regarding services and interventions for these difficulties is limited. This study explored viewpoints of key stakeholders, such as young people and frontline staff, about CSE services. Participants were recruited from services that support young people who have experienced CSE. The sample consisted of 18 participants; nine young people and nine professionals. Q-methodology was used to investigate subjective viewpoints regarding this topic. Statements about CSE interventions and services were collected from the existing literature and validated to form a Q-set. Participants sorted the Q-set from most to least important. Q-sorts were subjected to factor analysis using Q-methodology software. Three factors were identified: (1) The importance of safety and attunement, (2) Managing trauma and mental health difficulties and (3) Family, normality, and a relaxed approach. All factors emphasized the importance of safety and trust between young people and professionals. Key areas that may benefit service design were identified. Primarily, young people are likely to benefit from specialist support promoting a trauma-informed and relational approach.

Food restriction reduces neurogenesis in the avian hippocampal formation.

The mammalian hippocampus is particularly vulnerable to chronic stress. Adult neurogenesis in the dentate gyrus is suppressed by chronic stress and by administration of glucocorticoid hormones. Post-natal and adult neurogenesis are present in the avian hippocampal formation as well, but much less is known about its sensitivity to chronic stressors. In this study, we investigate this question in a commercial bird model: the broiler breeder chicken. Commercial broiler breeders are food restricted during development to manipulate their growth curve and to avoid negative health outcomes, including obesity and poor reproductive performance. Beyond knowing that these chickens are healthier than fully-fed birds and that they have a high motivation to eat, little is known about how food restriction impacts the animals' physiology. Chickens were kept on a commercial food-restricted diet during the first 12 weeks of life, or released from this restriction by feeding them ad libitum from weeks 7-12 of life. To test the hypothesis that chronic food restriction decreases the production of new neurons (neurogenesis) in the hippocampal formation, the cell proliferation marker bromodeoxyuridine was injected one week prior to tissue collection. Corticosterone levels in blood plasma were elevated during food restriction, even though molecular markers of hypothalamic-pituitary-adrenal axis activation did not differ between the treatments. The density of new hippocampal neurons was significantly reduced in the food-restricted condition, as compared to chickens fed ad libitum, similar to findings in rats at a similar developmental stage. Food restriction did not affect hippocampal volume or the total number of neurons. These findings indicate that in birds, like in mammals, reduction in hippocampal neurogenesis is associated with chronically elevated corticosterone levels, and therefore potentially with chronic stress in general. This finding is consistent with the hypothesis that the response to stressors in the avian hippocampal formation is homologous to that of the mammalian hippocampus.