1.
Leuk Res
; 35(12): 1571-7, 2011 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21752466
RESUMO
Plasmablastic lymphoma (PBL) is a rare aggressive B-cell lymphoproliferative disorder. HIV-negative PBL has not been extensively reported. Nine HIV-negative PBL patients evaluated at Moffitt Cancer Center were studied. Eight patients had extranodal diseases. All patients were treated with CHOP or hyper-CVAD. Responses were observed in 8 cases (7 complete, 1 partial responses). Four patients underwent consolidation with autologous hematopoietic stem cell transplant (HSCT) in first complete remission (CR1). At median follow-up of 23.9 months, 7 patients were alive and 5 were disease-free. Aggressive induction chemotherapy and consolidation with autologous HSCT in CR1 might be considered for patients with HIV-negative PBL.
Assuntos
Linfoma de Células B/terapia , Idoso , Terapia Combinada , Feminino , Seguimentos , Infecções por HIV/epidemiologia , Humanos , Imunofenotipagem , Linfoma de Células B/epidemiologia , Masculino , Pessoa de Meia-Idade , Indução de Remissão , Estudos Retrospectivos , Resultado do Tratamento
2.
Leuk Lymphoma
; 49(2): 350-2, 2008 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18231925