Detalhe da pesquisa
1.
Elucidating Compound Mechanism of Action by Network Perturbation Analysis.
Cell
; 162(2): 441-451, 2015 Jul 16.
Artigo
Inglês
| MEDLINE | ID: mdl-26186195
2.
Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.
Blood
; 129(1): 88-99, 2017 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27784673
3.
Systematic, network-based characterization of therapeutic target inhibitors.
PLoS Comput Biol
; 13(10): e1005599, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-29023443
4.
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials.
Proc Natl Acad Sci U S A
; 109(40): 16004-11, 2012 Oct 02.
Artigo
Inglês
| MEDLINE | ID: mdl-23012453
5.
Discovering Venom-Derived Drug Candidates Using Differential Gene Expression.
Toxins (Basel)
; 15(7)2023 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37505720
6.
Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators.
Cancer Cell
; 41(5): 933-949.e11, 2023 05 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37116491
7.
OncoLoop: A Network-Based Precision Cancer Medicine Framework.
Cancer Discov
; 13(2): 386-409, 2023 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36374194
8.
A Transcriptome-Based Precision Oncology Platform for Patient-Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies.
Cancer Discov
; 13(6): 1386-1407, 2023 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-37061969
9.
A Model for Network-Based Identification and Pharmacological Targeting of Aberrant, Replication-Permissive Transcriptional Programs Induced by Viral Infection.
Res Sq
; 2022 Feb 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35132404
10.
A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection.
Commun Biol
; 5(1): 714, 2022 07 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35854100
11.
TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas.
Clin Cancer Res
; 27(20): 5669-5680, 2021 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34433651
12.
Simulating henipavirus multicycle replication in a screening assay leads to identification of a promising candidate for therapy.
J Virol
; 83(10): 5148-55, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19264786
13.
The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies.
Elife
; 92020 09 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32945258
14.
The Host Cell ViroCheckpoint: Identification and Pharmacologic Targeting of Novel Mechanistic Determinants of Coronavirus-Mediated Hijacked Cell States.
bioRxiv
; 2020 May 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32511361
15.
Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma.
Cancer Res
; 79(9): 2415-2425, 2019 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30885979
16.
Tissue-Specific Analysis of Pharmacological Pathways.
CPT Pharmacometrics Syst Pharmacol
; 7(7): 453-463, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29920991
17.
Identification of Fluorescent Small Molecule Compounds for Synaptic Labeling by Image-Based, High-Content Screening.
ACS Chem Neurosci
; 9(4): 673-683, 2018 04 18.
Artigo
Inglês
| MEDLINE | ID: mdl-29215865
18.
A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors.
Nat Genet
; 50(7): 979-989, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29915428
19.
PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens.
Nat Commun
; 8(1): 105, 2017 07 24.
Artigo
Inglês
| MEDLINE | ID: mdl-28740083
20.
PI3Kγ/δ and NOTCH1 Cross-Regulate Pathways That Define the T-cell Acute Lymphoblastic Leukemia Disease Signature.
Mol Cancer Ther
; 16(10): 2069-2082, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28716817