Detalhe da pesquisa
1.
Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface.
J Virol
; 97(12): e0105223, 2023 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38032197
2.
Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.
Protein Expr Purif
; 179: 105796, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33221505
3.
Indole acids as a novel PDE2 inhibitor chemotype that demonstrate pro-cognitive activity in multiple species.
Bioorg Med Chem Lett
; 28(6): 1122-1126, 2018 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29534798
4.
Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4.
J Biol Chem
; 290(33): 20360-73, 2015 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26134571
5.
Structure of the bacterial deacetylase LpxC bound to the nucleotide reaction product reveals mechanisms of oxyanion stabilization and proton transfer.
J Biol Chem
; 288(47): 34073-34080, 2013 Nov 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24108127
6.
Structural basis for selective small molecule kinase inhibition of activated c-Met.
J Biol Chem
; 286(13): 11218-25, 2011 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21247903
7.
Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity.
J Am Chem Soc
; 134(30): 12342-5, 2012 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22793495
8.
Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.
J Virol
; 84(15): 7625-33, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20484498
9.
Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase.
BMC Struct Biol
; 10: 16, 2010 Jun 11.
Artigo
Inglês
| MEDLINE | ID: mdl-20540760
10.
Expression, purification and crystallization of human prolylcarboxypeptidase.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 66(Pt 6): 702-5, 2010 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20516604
11.
A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein.
Nat Commun
; 10(1): 4153, 2019 09 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31515478
12.
Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors.
Protein Sci
; 16(12): 2626-35, 2007 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-17965187
13.
Restoring methicillin-resistant Staphylococcus aureus susceptibility to ß-lactam antibiotics.
Sci Transl Med
; 4(126): 126ra35, 2012 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-22440737
14.
Structure of human prostasin, a target for the regulation of hypertension.
J Biol Chem
; 283(50): 34864-72, 2008 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-18922802
15.
Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses.
J Med Chem
; 51(20): 6503-11, 2008 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-18826204
16.
Biochemical and structural characterization of a novel class of inhibitors of the type 1 insulin-like growth factor and insulin receptor kinases.
Biochemistry
; 44(27): 9430-40, 2005 Jul 12.
Artigo
Inglês
| MEDLINE | ID: mdl-15996097
17.
Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificity.
J Biol Chem
; 277(41): 38797-802, 2002 Oct 11.
Artigo
Inglês
| MEDLINE | ID: mdl-12138114